Quality Control and Plant Location present by Waraporn Parnlob

1. Quality Control and Plant Location present by Waraporn Parnlob

2. Quality Control I Introduction in Quality Control IEffect of manufacturing process on Quality IRaw material control ILabeling and packaging material control

3. Quality Control (cont.) IIn -process and Production Control IThe Use of Statistical Quality Control IConclusion

4. What is the Quality control? “ An aggregate of activities designed to ensure adequate quality in manufactured products”

5. Effect of manufacturing process on Quality Major Aspect • Engineering and maintenance • The process

6. The Five Type a Raw materials aLabels a Packaging material a In process a Finishing product

7. They are termed variable because minor variations in anyone of these areas affects the other areas.

8. Raw material Control Raw material “ the solvents and chemical, whether active ingredient or inactive excipient, used in the manufacture of the dosage form.”

9. Raw material Control (Cont.) Raw materials, whether solids, liquids, or gases, all must be purified for use in drug products. Quality concern involve testing and inspection of - incoming solid - holding and distribution systems for liquids - distribution system for gas

10. The quality of the raw material is always defined by certain specification, with tests required to determine its identity, assay, quality,and purity using physical, chemical and microbiology procedures.

11. Labeling and Packaging material Control Labeling “ a display of written printed or graphic matter accompanying the product ” Packaging Material “ anything used in packaging a product ”

12. Labeling and Packaging control q Control by sampling and testing and use the statistical method in evaluation. q Maintenance and storage of each of the label and package.

13. In-process and production control In-process include premixes, granulations, bulk tablets or capsule. Also include in this classification are packaged products that require additional processing.

14. In-process and production control Production and control procedures should include all reasonable precautions to assume that the product has the safety, identity, strength , quality and purity.

15. The use of statistical quality control To increase productivity through total control of quality ; Control Chart assist in achieving this purpose.

16. Control Chart “ A graphical representation of variation that affect the quality of product.”

17. Control Chart use X Prediction of product quality trends X Provides a sound bases for establishing or change manufacturing specification X Improving, narrow or otherwise change minimum or maximum property limit

18. Upper control limit(max) Normal (average) Lower control limit (minimum)

19. Upper control limit = p + 3 (p(100-p)/n)1/2 Lower control limit = p - 3 (p(100-p)/n) 1/2 n = sample size p = average percent defection across many sample

20. Conclusion inputconversionoutput Raw materials and supplies Production Process Product Control chart

21. Conclusion lQuality control must use through out production system. lDeveloping control chart programs to monitor the process that meet customer expectation that is the basic for determining if product are of superior quality

22. Plant Location X General Information of Thailand X Factors Affecting Location X Conclusion

23. General Information 2 Geography 2 Topography 2 Climate 2 Population

24. Geography 1 Situated in the heart of the Southeast asia mainland 1 Long coastline on the Gulf of Thailand and the Indian ocean

25. Topography Thailand is divided into 4 natural regions. 3The North 3The Northeast 3The Central Plain 3The South

26. Climate ท Thailand is warm and rather humid tropical country. ท The average temperature is 28.1 ๐C

27. Population ม the population reached 62.1 million in 1999 ม The size of the work force exceed 32.9 million,with the majority of the workforce under 30 years of age. มEducation increased in recent years. It’s used to continue to increase into 21st century.

28. Population Minimum wage in Thailand

29. Factor Affecting Location 4 Infrastructure 4 Taxation 4 Labors Issues

30. Infrastructure ท Highways ท Water supply ท Electricity ท Railways ท Seaports ท Telephone services ท Airports

31. Taxation J Corporate Income Tax JExcite Tax JValue Added Taxes JImport Tariffs

32. Labors Issues MMinimun Daily Wage Rate MOvertime Regulation

33. Industrial Estates a Have Infrastructure that investigator want a Privilege in Taxation a Have labor enough to work in plant.

34. Industrial estate have 3 zones ,different in privilege .

35. Conclusion The suitable plant location of production group is in the third zone of Industrial estate and for comfortable communication will select Lam Cha Bung Industrial estate.

36. Thank you for your attention