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Non- Hodgkins Lymphoma

Non- Hodgkins Lymphoma. Clinical features. Non- Hodgkins Lymphoma. - heterogenous group of lymphoproliferative malignancies with differing patterns of behavior and responses to treatment -originates in the lymphoid tissues and can spread to other organs -More common in elderly and males.

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Non- Hodgkins Lymphoma

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  1. Non-Hodgkins Lymphoma Clinical features

  2. Non-Hodgkins Lymphoma -heterogenous group of lymphoproliferative malignancies with differing patterns of behavior and responses to treatment -originates in the lymphoid tissues and can spread to other organs -More common in elderly and males http://emedicine.medscape.com/article/202677-overview Harrison’s Principle of Internal Medicine 17th edition

  3. Lymphadenopathy • the most common manifestation of lymphoma • Waldeyer ring &mesenteric Lymph nodes are commonly involved • Spreads in noncontiguous fashion Robbins & Cotran Pathologic Basis of Diseases, 7th edition p. 686

  4. Ningetonaang script mo • The clinical presentation of the various lymphoid neoplasms is dictated by the anatomic distribution of the dse(Robbins & Cotran Pathologic Basis of Diseases, 7th edition p. 686)

  5. Lymphadenopathy • 2/3 of NHL (and virtually all cases of HL) present with NONTEDER nodal enlargement often >2cm size that can be localized or generalized • The remaining 1/3 of NHL’s arise at extranodal sites ( e.g. skin, stomach and brain) Robbins & Cotran Pathologic Basis of Diseases, 7th edition p. 668

  6. Ningetonaang script mo • This slide shows the other sgn/sx that is seen in NHL. Ning refer ka sa word doc nanakaattach specifically yung doc name ay “script”

  7. Other Signs And Symptoms • fevers, night sweats, weight loss, and fatigue • pruritus • shortness of breath, chest pain, cough, abdominal pain and distension, or bone pain • pallor (suggesting anemia) • purpura, petechiae, or ecchymoses (suggesting thrombocytopenia) http://emedicine.medscape.com/article/202677-overview Harrison’s Principle of Internal Medicine 17th edition

  8. Ningetonaang script mo • The following is a summary of the Different types oF NHL and their corresponding clininalfeatrues

  9. Robbins & Cotran Pathologic Basis of Diseases, 7th edition p. 671

  10. Robbins & Cotran Pathologic Basis of Diseases, 7th edition p. 671

  11. Robbins & Cotran Pathologic Basis of Diseases, 7th edition p. 671

  12. Ningetonaang script mo It is important to stress that

  13. Lymphoid neoplasia can be suspected from all the clinical features but histological examination of lymph nodes or other involved tissues is required for the diagnosis Robbins & Cotran Pathologic Basis of Diseases, 7th edition p. 668

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