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HIV-1 Infection Vs HIV-1 Antibody-Negative Individuals And Genotypic Markers. Jacinta Gaitor 2/15/02. Determination of Genotype Frequency among HIV-1 Infected versus Non-infected Individuals. Genomic DNA was screened by using 170 mapped polymorphic loci.
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HIV-1 Infection Vs HIV-1 Antibody-Negative Individuals And Genotypic Markers Jacinta Gaitor 2/15/02
Determination of Genotype Frequency among HIV-1 Infected versus Non-infected Individuals • Genomic DNA was screened by using 170 mapped polymorphic loci. • Distortion of allele and geneotype frequency among HIV-1 positive vs high risked HIV-1 negative persons were determined.
A Graph Showing Genotypic markers and HIV-1 infection [G test ]
Conclusion • According to the data displayed in the graph, CKR5 show a significant distortion of genotype frequencies among the infected vs uninfected. • The other loci (CD4, chemokine SCYAL, HLADQAL, TCRA,TCRB) on the other hand did not show such a significance.