40 likes | 200 Views
Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation. Osteoscoop - Issue N°272 – January 2013. + Wnt. Mesenchymal stem cell. Preosteoblast. Osteoblast. Bone formation. Wnt. LRP5/6. P. P. P. b - Catenin. b - Catenin. Nucleus.
E N D
Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation Osteoscoop - Issue N°272 – January 2013
+ Wnt Mesenchymal stem cell Preosteoblast Osteoblast Bone formation Wnt LRP5/6 P P P b-Catenin b-Catenin Nucleus
+ Wnt Mesenchymal stem cell Preosteoblast Osteoblast Bone formation Wnt N-Cadherin LRP5/6 P P P b-Catenin b-Catenin Nucleus
+ Wnt Mesenchymal stem cell Preosteoblast Osteoblast Bone formation D62-nCad Wnt N-Cadherin N-Cadherin LRP5/6 P P P b-Catenin b-Catenin 28aaLrp5 Nucleus