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Block Day- April 18, 2012. Homework : None Make an entry : Entry 37: Mitosis vs. Meiosis -4/18/12 Complete the chart. Mitosis vs. Meiosis. Mitosis Meiosis Mitosis Mitosis Meiosis Meiosis. Meiosis Meiosis Mitosis Meiosis Meiosis Mitosis Both. Make an entry.
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Block Day- April 18, 2012 Homework: None Make an entry: Entry 37: Mitosis vs. Meiosis-4/18/12 Complete the chart
Mitosis vs. Meiosis Mitosis Meiosis Mitosis Mitosis Meiosis Meiosis • Meiosis • Meiosis • Mitosis • Meiosis • Meiosis • Mitosis • Both
Make an entry Entry 38: Karyotypes-4/18/12 Definition: A karyotype is a picture of a person’s chromosomes.
In a karyotype, homologous pairs of chromosomes are matched and labeled. Cut out from picture and match each in pairs
How do we identify homologous chromosome pairs? • Size • Stain with a dye to produce a pattern of bands (banding pattern) • Position of the centromere Centromere
Gender determination • Females have 2 “X” chromosomes. • Males have 1 “X” and 1 “y” chromosome. X X Female X y Male
Why make karyotypes? • Some diseases are caused by problems with chromosomes • Extra chromosomes • Missing chromosomes • Broken chromosomes • Making karyotypes allows scientists to identify these diseases. Example karyotypes Using karyotypes to predict disease
Chromosomal Abnormalities • Caused by problems in Meiosis • Errors in Meiosis • Cannot be detected until the embryo (baby) is already made
Detecting Chromosomal Abnormalities Amniocentesis
Chromosomal Abnormalities • Some chromosomal abnormalities are linked to maternal age (Down’s Syndrome)
Amniocentesis • High-Risk mothers and mothers who have odd test results may get an Amniocentesis • An “amnio” is a sample of the amniotic fluid that surrounds the baby. This fluid contains the baby’s cells.
Amniocentesis • From the Amniocentesis, a karyotype can be made.
Normal (complete set of chromosomes) Disease (extra chromosome)
Karyotype Lab • Get a laptop, write down your number - log in to computer and wait! • Go to the pickup work folder and open the document “Links for Karyotype Lab” • Using the links- complete the fill in the blank notes on the chromosomal disorders: Down, Turner, and Kleinfelter syndromes.
When you are finished- Tape this into the Karyotype entry - Shut down your laptop