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Exercise 27. Gross Anatomy of the Heart BI 232. Mediastinum. The heart and pericardial cavity are located within the mediastinum, a centrally located area within the thoracic cavity. The Pericardium. Membranous sac
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Exercise 27 Gross Anatomy of the Heart BI 232
Mediastinum • The heart and pericardial cavity are located within the mediastinum, a centrally located area within the thoracic cavity.
The Pericardium • Membranous sac • 2 parts: outer fibrous pericardium that is fused to adjacent structures and an innerserous pericardium which is a delicate serous membrane that forms a double-layered sac around the heart. • The serous pericardium consists of parietal and visceral layers.
The heart • Two-sided, double-pumping organ. • The left side controls the flow of blood to all tissues and cells in the body, where oxygen and nutrients are delivered and wastes are taken away. • The right side sends blood to the lungs, where oxygen stored in RBCs is replenished and CO2 is released
Coronary Circulation • On the posterior surface of the heart, the coronary artery branches to become the posteriorinterventricular artery • Near the apex of the heart the anterior and posterior interventricular arteries form an anastomosis (connection)
Coronary Circulation • On the posterior surface of the heart, the coronarysinus runs along the coronary sulcus and empties into the right atrium. • Great cardiac vein found in the anterior interventricularsulcus • Middle cardiac vein ascends along the posterior interventricular groove
Blood flow Through the Heart • Pulmonary Circulation- Blood from the right side of the heart flows to and from the lungs • Systemic Circulation- Blood from the left side of the heart flows from and to all body tissues.
Position of Heart • Base of the heart extends from the inferior border of the second costal cartilage on the left side to the superior border of the third costal cartilage on the right. • Apex of the heart is located in the left fifth intercostal space, left of the median plane
Heart: muscular pump • Actually 2 pumps acting in unison • Systole is contraction of heart muscle • Atrial systole • Ventricular systole • Diastole is relaxation of heart muscle • Atrial diastole • Ventricular diastole
Conduction system of the Heart (Exercise 32) • Electrical activity of the heart stimulates the heart muscle to contract. • Sinoatrial (SA) node = pacemaker of the heart • Atrioventricular (AV) node: there is a slight delay (0.10 second) • Atrioventricular bundle (bundle of His) • Right and left bundle branches • Purkinje fibers: stimulate cardiac muscle of the ventricles to contract http://youtu.be/te_SY3MeWys
Electrical activity of the Heart • Heart produces low-voltage electrochemical impulses • The average potential difference is -90 millivolts • These impulses can travel through the saline medium of the body and be picked up by sensors attached to the skin • The collective action potentials generated by the atria and ventricles depolarizing and repolarizing can be recorded using an electrocardiograph machine
P wave • The P wave indicates the depolarization of the atria just prior to the beginning of atrial contraction or systole
QRS complex (QRS interval) • Represents the depolarization of the ventricles which precedes ventricular systole.
T wave • Results from ventricular repolarization, which occurs before ventricular relaxation or diastole.
Analysis of the ECG • Irregularities in Heart rate: • Tachycardia: Above 100 in adults (in small children this may be normal) • Bradycardia: in young adults below 60 beats per minute (unless person is highly trained aerobic athlete)
Heart Blocks • PR intervals are normally about 0.16 second. • Time between the beginning of atrial depolarization and the beginning of ventricular depolarization. • Long PR might indicate a heart block (reduced conduction between atria and ventricles) • Longer than 0.2 second • Complete heart block the atria do not stimulate ventricular depolarization at all, so atria fire independently of ventricles
Heart Blocks • Normal QRS is 0.08 to 0.10 second on average. • Longer than 0.12 may indicate a right or left bundle branch block • QT interval is normally about 0.3 second • This is shorter as the heart rate increases and longer as heart rate slows.
Cardiac Arrhythmias • A major diagnostic use is to detect arrhythmias, abnormal rhythms of the heart • Atrial fibrillation: electrical activity of the heart is uncoordinated causing the upper chambers to quiver. • Ventricular fibrillation: where electrical signals in the ventricles fire in a very fast uncontrolled manner. • Premature ventricular contraction (PVC): electrical signal causes an early heartbeat that usually goes unnoticed
Today’s lab • Dissect sheep heart • ID structures on the heart models • We will also be doing EKGs (We will be using the Vernier EKGs rather than the BIOPAC machines mentioned in the lab manual) • After performing your EKG follow the instructions in your lab manual and calculate the mean electrical axis of your heart
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