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Cardiovascular Disease. Risk and Treatment . CVD Classes of Risk Factors. Inherent Physiological Psychosocial. Inherent Risk Factors. Inherited Risks Family History of CVD Genes Gender to some extent Unclear why Glucose metabolism We’ll talk in Chapter 11 Ethnicity
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Cardiovascular Disease Risk and Treatment
CVD Classes of Risk Factors • Inherent • Physiological • Psychosocial
Inherent Risk Factors • Inherited Risks • Family History of CVD • Genes • Gender to some extent • Unclear why • Glucose metabolism • We’ll talk in Chapter 11 • Ethnicity • Reason a likely due to other risks
Physiological Conditions • Hypertension • Single biggest risk factor for MI and CVA • Hypercholesterolimia • Ratio now seen as more important predictor than cholesterol level alone • HDL should be 22% of total for men and 25% of total for women • Increase HDL • Exercise • Moderate alcohol consumption • Decrease LDL • Less saturated fat • More vegetables • Hyperlipidemia – Elevated fat in blood • Triglycerides
Psychosocial/Behavioral Factors • Education and Income • Negative correlation • Smoking • Leading behavioral risk factor • Have begun to decline as smoking rates decline (Chapter 2) • Diet • Anxiety & Depression • After controlling for other risk factors there is a positive correlation • Type A - Hostility/Anger • Marriage and Social Support
Type A Behaviors • Hostile, cynical • Judgmental (opinionated) • Competitive • Time urgent • Uses gestures while talking • Nodding of head while others are talking • Intense
Type A to CVD • Hostility – Cynical mistrust, resentment • Predictive but not independent • Anger – Expressed hostility to others • Independent predictor • Expression of anger is the key
Cardiovascular Reactivity • Physiological and cardiovascular reactivity to acute stress • Exaggerated increases in blood pressure, heart rate, catecholamines, corticosteroids • High levels of these hormones can damage heart and blood vessels • Presence of epinephrine (a catecholamine) increases the formation of clots. • CVR may be part of the difference between AA and Caucasians
Marriage and Social Support • Being single and lacking social support is a risk factor for some • Three years after MI, those with high stress and low social support had four times the death rate. • Living alone after one heart attack triples the chances of having another and dying • Loneliness lack of companion related to CVD in elderly. • Elevated risk of death from CVD in women who perceive low support at work and home even when controlling for physiological risk factors.
Public Health Model and CVD • AGENT – Cigarette Smoke, Cholesterol, Saturated Fat • HOST – Hostility/CVR, Family History, African American, Exercise, Income, Education • ENVIRONMENT – Social Support, Awareness,
Treatment • Medical • Psychosocial
Medical Treatment • Risk management - Medications • Control of high blood pressure • Control of lipid abnormalities
Medical Treatment • Initial treatment may involve clot-dissolving medication and close monitoring • Balloon angioplasty • Tiny balloon is inserted into blocked vessel and inflated to open blood vessel • Bypass surgery • Use grafted vessel (e.g., piece from leg) to bypass blockage in artery to the heart
Psychosocial Rehabilitation • Exercise • Physiological and psychological benefits • Weight management • Smoking cessation • Dietary changes to control lipids and cholesterol • Reduce excessive alcohol intake • Stress management • Support groups
Psychosocial Rehabilitation • Exercise is the key component but: • 50% drop-out rate within first 6 months • For those who continue benefits include: • Improved self concept, perceived health, sexual activity, involvement in social activities. • Those who stop are more likely to: • Smoke, have poorer cardiac function, have higher body weight, be more sedentary, experience greater anxiety and depression.