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Ch 36 Musculoskeletal System . AP lecture. Three vertebrate muscles. Skeletal A.k.a striated Voluntary movements . Cardiac Involuntary Beating of the heart Appears striated because of myosin and actin Smaller than skeletal Cells attached by gap junctions . Smooth Involuntary
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Ch 36 Musculoskeletal System AP lecture
Three vertebrate muscles • Skeletal • A.k.a striated • Voluntary movements
Cardiac • Involuntary • Beating of the heart • Appears striated because of myosin and actin • Smaller than skeletal • Cells attached by gap junctions
Smooth • Involuntary • Movement of internal organs • Internal organs controlled by ANS • Smaller than skeletal • Do not appear striated because of the actin and myosin arrangements
Muscle contraction • Skeletal muscle cells and muscle fibers are bundled together by connective tissue • Interactions between actin and myosin • Every muscle fiber is made of myofibrils- actin and myosin in repeating segments called sarcomeres
Muscle involuntary, striatedauto-rhythmic voluntary, striated heart moves bone multi-nucleated involuntary, non-striated digestive systemarteries, veins evolved first
Actin • Thin filaments • Long chains of actin monomers twisted around each other. • Twisted around that chain is tropomyosin and attached to that is troponin. • These control contractions and relaxation
Myosin • Two long polypeptide chains coiled together. Each ends in a large globular head. • Myosin filaments have many myosin molecules
http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter10/animation__myofilament_contraction.htmlhttp://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter10/animation__myofilament_contraction.html
ATP feeds the contractions • Immediate system uses ATP • Glycolytic system metabolizes carbohydrates to lactate and pyruvate • Oxidative system metabolizes carbohydrates or fats into water and carbon dioxide
formcrossbridge releasecrossbridge shortensarcomere Where is ATP needed? binding site CleavingATP ADP allows myosin head to bind to actin filament thin filament(actin) myosin head ADP 1 thick filament(myosin) 2 ATP 1 1 3 1 1 4
Put it all together… 1 2 3 ATP 7 4 6 ATP 5
Vertebrate skeleton • 206 bones • Axial skeleton • Skull, vertebral column ,sternum and ribs • Appendicular skeleton • Pectoral girdle, pelvic girdle, arm, leg, hands and feet bones
Joints • Two bones join and muscles work in antagonistic pairs • Flexor • Extensor • Types of joints • Ball and socket • Pivot • Hinge
Tendon • Ligament