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Explore the pivotal experiments by Griffith, Avery, Hershey, and Chase that established DNA as the genetic material, shaping our understanding of heredity. Delve into the impact of their findings on genetic research. Engage with the fascinating journey of unraveling the essence of life.
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Discovery of DNA Griffith’s Conclusion: “something” transformed the harmless bacteria into the deadly bacteria. (He called this process transformation) Oswald Avery – repeated Griffith’s work to determine which molecule was responsible for transformation • Conclusion: DNA was the transforming factor that caused the change in the R-strain
Discovery of DNA Alfred Hershey & Martha Chase • Question: Are genes made of DNA or proteins? • What they knew: • viruses use other organisms to reproduce • Viruses only contain DNA and a protein coat. • Whichever virus particle enters the cell must be the material that makes up genes (DNA).
Discovery of DNA Hershey and Chase • Experiment: • They tagged the virus DNA with blue radioactive phosphorous • They tagged the protein coat with red radioactive sulfur • Results: • the cells only contained blue radioactive phosphorous. • Conclusion: • Virus only injects DNA (confirms Avery’s results) http://highered.mcgraw-hill.com/olcweb/cgi/pluginpop.cgi?it=swf::535::535::/sites/dl/free/0072437316/120076/bio21.swf::Hershey%20and%20Chase%20Experiment