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The Discovery of DNA

The Discovery of DNA. BY : Kassandra Kimbler U.S History Class Mr. Ostrander . The people that discovered DNA.

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The Discovery of DNA

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  1. The Discovery of DNA BY : Kassandra Kimbler U.S History Class Mr. Ostrander

  2. The people that discovered DNA Many people think when it comes to DNA that James Watson and Francis Crick were the first to discover DNA. This is not true the first to discover DNA was Friedrich Miescher. Miescher, Phoebus Levene, and Erwin Chargaff they all together studied and carried out the research of the DNA molecule. They found out how they joined together. With out there ground braking information Watson and Crick may have never found out that DNA consist in the form of a double helix. James Watson and Francis Crick Friedrich Miescher Phoebus Levene Erwin Chargaff

  3. How it Started! In the year 1869 it was a land marked year for the research of genetics. This year a Swiss chemist Friedrich Miescher discovered that inside a nuclei of a human was a nuclein which was later changed to a nucleic acid but we call it deoxyribonucleic acid or more comely known as DNA. Miescher wanted to find a way that he could isolate the protein not the nuclide. To do this he needed pus-coated bandages so he made planes for a local surgeon to send him bandages. When he got the bandages he diced to wash them to separated the leukocytes from the protein in the white bold cells. Leukocytes A strand of DNA

  4. How it Started Continued When Miescher separated the leukocytes form the white blood cells he discovered that in the nuclei call there was a chemical property that was unlike any other protein. When he saw this Miescher noticed that he had discovered a new substance. When he discovered this he wrote “ It seems probable to me that a whole family of such slightly varying phosphorous-containing substances will appear, as a group of nucleins, equivalent to proteins.” Miescher’s work went unappreciated for nearly fifty years tell it was appreciated in the science community. Phosphorous

  5. Phoebus Levene Phoebus Levene started to work on new information for the molecule nuclein. Levene was the first to discover many things like the three components of a nucleotide, the carbohydrate of the component RNA and DNA, and he also discovered how RNA and DNA are related and put together. RNA RNA and DNA Nuclein

  6. Levene Investigates the Structure of DNA Levene discovered that each nucleotide meant that there were different ways in witch the components would be able to combine. Many scientists stated on how they could combine but Levene had put together a “polynucleotide” modal that was correct. Levene said that each nucleotide was contained of one of the four nitrogen-containing basses a sugar molecule, and also a phosphate group. Nitrogen-bases

  7. Levene Investigates the Structure of DNA Continued Levene also discovered the way that the nucleotides are in odder. He also found out that the nucleotides are always linked in the same odder no matter what (EX: G-C-T-A-G-C-T-A and so on). This proved to be accurate in many regards.

  8. What we Know Now We now know that the DNA structure in composed of nucleotides and that each one has three components. Those three are the phosphate group (ribose or a deoxyribose sugar), and a single nitrogen-containing base. There is also two nitrogenous bases they are adenine [A], and guanine [G]. The nitrogen basses than combine with cytosine [C], thymine [T], and uracil [U]. How ever RNA only has A,G, C, and U. How ever DNA contains A, G, C, and T. How DNA and RNA join

  9. Watson and Crick After Chargaff’s discovery that A=T and C=G Watson and Crick found out that DNA was a three-dimensional double-helical. To make this modal they moved the molecules around on there desktops. They were confused on how guanine and thymine joined to getter. The very first DNA modal was made out of cardboard cut outs. DNA

  10. Since than since the discover of DNA and RNA we now know that DNA is in the form of a double-stranded helix. We also know that DNA is right-handed. DNA is an anti-parallel double-helix. We also know that the bases in DNA bind by hydrogen bonding. What DNA looks like now!

  11. My Source • http://www.nature.com/scitable/topicpage/Discovery-of-DNA-Structure-and-Function-Watson-397

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