1 / 25

Lecture 09 – Second Messengers III – cADPribose & Inositol lipid signaling

Lecture 09 – Second Messengers III – cADPribose & Inositol lipid signaling. BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F. CSB Fig 02:01 Cell signalling pathways .

feivel
Download Presentation

Lecture 09 – Second Messengers III – cADPribose & Inositol lipid signaling

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Lecture 09 – Second Messengers III – cADPribose & Inositol lipid signaling BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F

  2. CSB Fig 02:01 Cell signalling pathways Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  3. Transducers Second Messengers II • Cyclic ADPribose • ADP Ribosylcyclase • Inositol phosphate & other lipid signaling • PLC – PIP2, DAG • PI3K – PIP3 • PLD – PA

  4. CSB Fig 2:22 cADPR metabolism Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  5. CSB Fig 2:26 NAADP structure Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  6. CSB Fig 2:23 cADPR/NAADP function Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  7. Transducers Second Messengers II • Calcium signaling • Cyclic ADPribose • Inositol phosphate & other lipid signaling • PLC – PIP2, DAG • PI3K – PIP3 • PLD – PA

  8. CSB Fig 2:30 Phosphoinositidesignalling systems Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  9. CSB Fig 2:27 Phosphoinositide metabolism Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  10. CSB Fig 2:28 PtdIns structure Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  11. CSB Fig 2:29 PI 3-K family Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  12. CSB Fig 2:31 Inositol phosphate metabolism Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  13. CSB Fig 2:32 InsP3 and DAG formation Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  14. CSB Fig 2:33 InsP3 and DAG formation Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  15. CSB Fig 2:34 InsP3/Ca2+ signalling functions Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  16. CSB Fig 2:35 InsP3/DAG recycling Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  17. CSB Fig 2:36 PLC structure and function Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  18. CSB Fig 2:37 PKC structure and activation Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  19. CSB Fig 2:38 Localized inositol lipid signalling Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  20. CSB Fig 2:39 PtdIns4,5P2 signalling Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  21. CSB Fig 2:40 PtdIns4,5P2 regulation of K+ channels Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  22. CSB Fig 2:41 PtdIns4,5P2 regulation of TRP channels Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  23. CSB Fig 2:42 PtdIns 3-kinase signalling Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  24. CSB Fig 2:43 Insulin receptor Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

  25. CSB Fig 2:44 PIKfyve activation Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012

More Related