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Edge profile of commercially available square-edge intraocular lenses

Edge profile of commercially available square-edge intraocular lenses. Mayank A. Nanavaty 1 David J. Spalton 1 James Boyce 2 Anthony Brain 2 John Marshall 2. 1. St. Thomas’ Hospital, London 2. King’s College, London. Financial interests: None. Aim.

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Edge profile of commercially available square-edge intraocular lenses

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  1. Edge profile of commercially available square-edge intraocular lenses Mayank A. Nanavaty1 David J. Spalton1 James Boyce2 Anthony Brain2 John Marshall2 1. St. Thomas’ Hospital, London 2. King’s College, London Financial interests: None

  2. Aim To analyze the sharpness of the posterior optic edge of intraocular lenses (IOLs) marketed with a ‘square-edge’ profile. Methods • Seventeen IOLs of different designs and material all marketed as ‘square-edge’ IOLs • 20 Diopter IOL of each selected • IOLs examined with environmental scanning electron microscopy

  3. FEI Quanta 200F field emission gun environmental scanning electron microscope was used to examine IOLs • Parameters standardized for all IOLs • 93.3 Pascal (0.7 torr), • Specimen temperature of 20oC, • Voltage of 15 KV • Magnification x 500 • Average processing time 25 minutes IOLs mounted using a simple microscope Haptic excised Some IOLs required cutting of the haptic and/or optic to view edge Posterior edge appears always on the left

  4. Measurement of Radius of Curvature of Posterior Optic Edge Customised computer program measures the local radius of curvature L L P P R r R r Sharper optic edge = Smaller r See details in J Cataract Refract Surg, April 2008.

  5. Hydrophobic Acrylic IOLs 9.9µ 9.3µ 8.5µ Alcon AcrySof IQ Alcon AcrySof Natural Alcon AcrySof MA60AC

  6. Hydrophobic Acrylic IOLs 8.3µ 19.9µ Hoya AF-1(UY) AMO Sensar AR40e

  7. Hydrophilic Acrylic IOLs 15.9µ 14.3µ B & L Akreos B & L MI60 23.1µ 15.5µ Rayner Superflex Lenstec Tetraflex

  8. Hydrophilic Acrylic IOLs 9.1µ 8.6µ Human Optics 1CU Human Optics MC611 MI-B

  9. Silicone IOLs 7.6µ 8.3µ Bausch & Lomb Soflex SE Bausch & Lomb SofPort AO

  10. Silicone IOLs 9.2µ 8.3µ 9.0µ AMO Tecnis Z9000 AMO Clariflex AMO Tecnis ZM9000

  11. Summary Radii of curvature (µ) Hydrophobic Acrylic IOLs Hydrophilic Acrylic IOLs Silicone IOLs

  12. Conclusion • Commercially marketed ‘square edge’ IOLs differ in posterior edge sharpness. • Most hydrophobic acrylic and silicone IOLs have sharper posterior optic square edges compared to most hydrophilic acrylic IOLs. This probably reflects difference in manufacturing techniques. • The difference in the posterior optic edge profile may explain why some IOLs have relatively poor PCO performance and may explain why some IOL materials appear to have better PCO performance than others.

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