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Group I. Group II. Online Supplemental Data. frameshift. in frame del. positive. negative. missense. negative. frameshift. positive. missense. A. B. A287LfsX191. E383_L387>YfsX91. H289delfsX188. N456del. K457SfsX21. Y259D. R331Q R331P. R571C (lamC). L512P. R377H. E33D.
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Group I Group II Online Supplemental Data frameshift in frame del positive negative missense negative frameshift positive missense A B A287LfsX191 E383_L387>YfsX91 H289delfsX188 N456del K457SfsX21 Y259D R331Q R331P R571C (lamC) L512P R377H E33D Y267C R527P R11AfsX83 E347K N39S T528K R388C R249Q S573L (lamA) K32del E358K R453W W498C protein 1 664 1A 1B 2A 2B Ig fold CAAX NLS mRNA 12 10 1 2 3 4 5 6 7 8 9 11 C Figure E-1