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THE UTILITY OF APACHE II SCORE IN PREDICTING THE OUTCOME OF SEVERE INFECTIONS

THE UTILITY OF APACHE II SCORE IN PREDICTING THE OUTCOME OF SEVERE INFECTIONS. First Author: Ráduly Kinga Author: Ráduly Orsolya Coordinators: Dr. Zaharia Kézdi Iringo, Dr. Nina Sincu. Introduction.

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THE UTILITY OF APACHE II SCORE IN PREDICTING THE OUTCOME OF SEVERE INFECTIONS

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  1. THE UTILITY OF APACHE II SCORE IN PREDICTING THE OUTCOME OF SEVERE INFECTIONS First Author: Ráduly KingaAuthor: Ráduly Orsolya Coordinators: Dr. Zaharia Kézdi Iringo, Dr. Nina Sincu

  2. Introduction • APACHE II was designed to measure the severity of disease for adult patients admitted to Intensive care units, for patients aged 15 or older. • This scoring system is used in many ways: • can be used to describe the morbidity of a patient when comparing the outcome with other patients • predicted mortalities are averaged for groups of patients in order to specify the group’s morbidity.

  3. The Estimated Risk of Hospital Death (ERHD), based on APACHE II score: • > 35% for APACHE II score > 20 pt • 11-35% for APACHE II score of 10-20 pt • < 11% for APACHE II score < 10 pt

  4. Methods • We have conducted a retrospective, descriptive, transversal study on a sample of 29 patients admitted to Infectious Diseases Clinic I from Tg-Mures, during 2009-2010. • The study included patients aged 16 or older, diagnosed with an infectious disease, who required intensive care treatment. • We analyzed the patients’ files and calculated the APACHE II score. • The results were analyzed by using a statistic programme (GraphPad)

  5. The distribution of the apache ii scoring of patients

  6. Distribution of patients by apache ii score Age over ≥ 65 years: 6 out of 8 patients have deceased (75%) < 65 years: 9 out of 21 patients (42.85%) P 0.2148 - we did not find statistically significant association RR: 1.750 CI 95%= 0.9267-3.305

  7. the average age and the apache ii score

  8. Mortality rate reported to apache ii score • Mortality rate: • 84.16% for APACHE II > 20 pt • 30.76% - APACHE II 10-20 pt • 0% - APACHE II < 10 pt

  9. Main diagnosesapache ii score > 20 pt

  10. Main diagnosesapache ii score 10-20 pt

  11. Main diagnoses apache ii score < 10 pt

  12. Conclusions • The mortality rate was higher than expected in patients with APACHE II score > 20 pt (84.16 % compared with an ERHD > 35 %) • We did not find statistically significant association between advanced age (over 65 years old) and mortality rate (p=0.2148). • The severe illnesses, such as severe sepsis and respiratory impairment were associated with worse outcome.

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