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The 3 Steps of X Inactivation. Initiation. One of the two X Chromosomes are randomly selected to be the inactivated X Chromosome and the activated. This occurs during Embryonic Development. XIC. What’s this?. XIC. Somatic Cell. The XIC is the area where the X Chromosome is inactivated .
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Initiation One of the two X Chromosomes are randomly selected to be the inactivated X Chromosome and the activated. This occurs during Embryonic Development. XIC What’s this? XIC Somatic Cell
Spreading XIST (Gene) Encodes=> RNA XIC XIC Once the RNA is encoded by the xist, the rna coats the chromosome enacting it to compact
Once the X Chromosome completely changes shape, it is called a Barr Body.
Maintenance The Bar Body is replicated like the activated X Chromosome, though it essentially stays inactive.
Keep in mind, any cell that derives from this cell will have the same X Chromosome inactivated.