410 likes | 620 Views
TREATMENT PLANNING PHOTONS & ELECTRONS. Karen P. Doppke 3/20/2007. Regions of Radiation Field Considered in Dose Calculations. DOSE TO A POINT IN TISSUE. Major Processes that Effect Dose in Tissue from Photon Beams Inverse Square Law Photon Attenuation Photon Scatter.
E N D
TREATMENT PLANNING PHOTONS & ELECTRONS Karen P. Doppke 3/20/2007
DOSE TO A POINT IN TISSUE Major Processes that Effect Dose in Tissue from Photon Beams Inverse Square Law Photon Attenuation Photon Scatter
Dose Calculation Methods Used to Determine Dose at a Point in a Patient Model Based Methods Pencil Beam Methods Convolution Superposition Monte Carlo Calculations Correction Based Methods % Depth Dose Calculations Tissue Maximum/Phantom Ratios Tissue-Air Ratios
The General Form of Equation Used to Calculate Dose at Depth in the Patient TPR (d, r, h) = Dose at Depth / Dose at Reference/Max
Conformal Planning Process PATIENT DATA SET/S CT, MRI, PET DEFINATION OF TARGET AND NORMAL TISSUES PRESCRIPTION DOSE and FRACTIONATION TOTAL DOSE TO VOLUMES DOSE TO NORMAL TISSUES
EXAMPLE OF A CONFORMAL PLAN The prescription should include the total dose to the target volumes, the fractionation, a statement of the expansion of the GTV to the CTV and PTV. The dose limits to the normal tissues that are near the site of treatment need to be defined.
TREATMENT VOLUMES GTV CTV ITV PTV
NORMAN TISSUES NEAR TREATMENT SITE SPINAL CORD < ~45 Gy LIVER <~25Gy/100%, 30Gy/35%, 35Gy/25% KIDNEYS <~23Gy/66% LUNG <~30Gy/40%, 60Gy/20% HEART <~30Gy/100% LV, 45Gy/100% (atrium)
DVH FOR TISSUES AP/PA CTV PTV Liver Lung RT Kidney RT Heart
DVH 4 FIELD PLAN CTV PTV Liver Heart Kidney RT Lung RT
DVH 5 FIELD PLAN CTV PTV Liver Lung RT Heart Kidney RT
CTV Lung RT Kidney RT
Stereotactic Radiosurgery • 1905: Introduction of stereotactic equipment • 1908: Mapping of brain in 3 planes • 1918: First stereotactic frame for humans in London • 1940: Greatest strides in intracranial applications began
Stereotactic Radiosurgery 1982: Modified Linear Accelerator
Stereotactic Radiosurgery SRS Frame Placement
Fractionated Stereotactic Radiation Therapy Fractionated Stereotactic Radiation Therapy(SRT) combines the target and dose localization characteristics of SRS with the biologic advantages of dose fractionization