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Growth and Physical Training with Reference to Heredity. WEBER, G., W, KARTODIHARDJO, AND V. KLISSOXJRAS, J Appl. Physiol. 40(2): 211-215. 1976. Presented by Ryan Dalton. Background. Physiological responses to exercise vary with age Older men cannot improve as much as younger men
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Growth and Physical Training with Reference to Heredity WEBER, G., W, KARTODIHARDJO, AND V. KLISSOXJRAS, J Appl. Physiol. 40(2): 211-215. 1976. Presented by Ryan Dalton
Background • Physiological responses to exercise vary with age • Older men cannot improve as much as younger men • Can function be improved at an earlier stage of maturation vs. at a later stage?
Background • Perhaps hormonal activity during growth overcomes any effects of exercise • In animal studies growth hormone causes equal increases in skeletal muscle in exercising animals and in their controls
Observation • There is pronounced development in adolescents who participate in sports compared to those who do not participate • Possible causes include: Genetics, Growth, and Training at different ages.
Limitations • Cross-sectional and longitudinal studies do not address how much of a factor genetics has in a child's development • The split-twin method was used to correct this problem, because each trained twin has a genotypically identical control
Purpose • To study the effects of training on the oxygen transport system of children, apart from the effects of growth
Methods • 12 pairs of identical twin boys were used • 4 pairs 10 years old • 4 pairs 13 years old • 4 pairs 16 years old
Training • One twin exercised while the other acted as the control • 10 weeks of endurance training • 1) 3 times a week running 1 mile at maximal effort • 2) 3 times a week of continuous stepping for an average of 8.5 mins and an average heart rate of 162 beats/min
Training • 3) 1 time a week cycling at 60 rpm for 3 mins which induced maximal heart rates • During recovery the work rate was reduced until heart rate returned to ~150 beats/min • “This work/recovery pattern was carried on until exhaustion”
Training • On average once per week the subjects trained for hockey or rugby • The control twin continued their usual daily activities and P.E. classes
Testing • Tests were conducted on a cycle ergometer before and after training • A series of progressive work loads were performed lasting for 5 min and 15 sec each, followed by a supramaximal effort of shorter duration • The twins exercised alternately motivating them to exert themselves to exhaustion
Measurements • VO2 – Gas Analyzer • Blood Lactate – Arterialized sample • Heart Rate – Electrocardiogram • Cardiac Output – Estimated by CO2 rebreathing • Vital Capacity - Respirometer • Lean body weight – Predicted from skinfold measurements
Results • All the variables for both twins changed • In the exercised twins: • 10 year olds – VO2 max changed significantly • 13 year olds – No significant changes • 16 year olds – VO2 max, O2 pulse, blood lactate, ventilation, respiratory frequency, and ventilation/vital capacity ratio changed significantly
Discussion • The lack of change in the 13 year old groups is interesting • The possible reason for no differences between the trained and controls is that during growth spurts hormones override any effects of exercise • Other studies have supported the lack of differences between trained and control subjects of this age
Extension of the study • The annual increase in the height of the 13 year olds was 8 cm • This rate of growth is expected only at the adolescent growth spurt • Because of the growth spurt the duration of training might be too short so the study was extended to a year for 3 pairs of the 13 year old twins
Discussion • The old idea that training a child at their greatest rate of growth to make even greater improvements seems incorrect based on the evidence in this study • Another question is if different genotypes respond to a training stimulus at different magnitudes
Discussion • According to the findings of this study improvements in VO2 max are highly based on heredity and exercise • But the findings do not support the interaction between the two
Conclusion • Children of young ages respond to training apart from normal growth • During puberty the effect of training seems to be negated • Variability in VO2 max seems to be based almost entirely on heredity, but can be lessened to about 50% from influences such as training