1 / 8

Original Article Childhood Body-Mass Index and the Risk of Coronary Heart Disease in Adulthood

Original Article Childhood Body-Mass Index and the Risk of Coronary Heart Disease in Adulthood. Jennifer L. Baker, Ph.D., Lina W. Olsen, Ph.D., and Thorkild I.A. Sørensen, M.D., Dr.Med.Sci. N Engl J Med Volume 357(23):2329-2337 December 6, 2007. Study Overview.

gyan
Download Presentation

Original Article Childhood Body-Mass Index and the Risk of Coronary Heart Disease in Adulthood

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Original ArticleChildhood Body-Mass Index and the Risk of Coronary Heart Disease in Adulthood Jennifer L. Baker, Ph.D., Lina W. Olsen, Ph.D., and Thorkild I.A. Sørensen, M.D., Dr.Med.Sci. N Engl J Med Volume 357(23):2329-2337 December 6, 2007

  2. Study Overview • In this Danish study, body-mass index in childhood was associated with coronary heart disease (CHD) events in adulthood • The association was stronger in boys than in girls, and the risk of an event in adulthood increased in both sexes as the child's age increased from 7 to 13 years • These important data focus attention on the public health significance of the epidemic of childhood obesity

  3. Mean BMI Values for 276,835 Children 7 to 13 Years of Age Baker JL et al. N Engl J Med 2007;357:2329-2337

  4. Body-Mass Index (BMI) in Childhood and the Risk of Coronary Heart Disease (CHD) in Adulthood Baker JL et al. N Engl J Med 2007;357:2329-2337

  5. Adjusted Hazard Ratio for the Risk of a Fatal or a Nonfatal CHD Event in Adulthood in Relation to a 1-Unit Increase in BMI z Score in a Cohort of 276,835 Children Baker JL et al. N Engl J Med 2007;357:2329-2337

  6. Adjusted Hazard Ratio for the Risk of Any CHD Event in Adulthood in Relation to a 1-Unit Increase in BMI z Score in Models Unadjusted and Adjusted for Birth Weight in a Cohort of 208,433 Children Baker JL et al. N Engl J Med 2007;357:2329-2337

  7. Predicted Risk of Having a CHD Event between 25 and 60 Years of Age in a Cohort of 276,835 Children of Average or Higher-Than-Average BMI Baker JL et al. N Engl J Med 2007;357:2329-2337

  8. Conclusion • Higher BMI during childhood is associated with an increased risk of CHD in adulthood • The associations are stronger in boys than in girls and increase with the age of the child in both sexes • Our findings suggest that as children are becoming heavier worldwide, greater numbers of them are at risk of having CHD in adulthood

More Related