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Komplexní spliceosom u LECA

Komplexní spliceosom u LECA. Collins & Penny, 2005. Na introny bohatý LECA (LECA = last eukaryotic common ancestor). Ribosomální protein L37. Rekonstrukce evoluce intronů v 684 KOG. Rogozin et al., 2003. Č asn ý vznik minoritn í ho U12-typu intron ů. Russell et al., Nature 2006.

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Komplexní spliceosom u LECA

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  1. Komplexní spliceosom u LECA Collins & Penny, 2005

  2. Na introny bohatý LECA (LECA = last eukaryotic common ancestor) Ribosomální protein L37 Rekonstrukce evoluce intronů v 684 KOG Rogozin et al., 2003

  3. Časný vznik minoritního U12-typu intronů Russell et al., Nature 2006

  4. Časová relace invaze intronů a genových duplikací Sverdlov et al., 2007

  5. Překvapení: propast mezi DNA replikací u eubakterií a archebakterií/eukaryot

  6. Meiosa (a sex?) nejspíš už u LECA Ramesh et al., Curr Biol 2005

  7. Evoluce chromatinu - histony b: Methanothermus HMfA homodimer c: Methanopyrus doublet histon d: H3-H4 heterodimer e: H2A-H2B heterodimer

  8. Chromatin obrněnek Dinokaryon

  9. b-D-glucopyranosylhydroxymetyluracil – báze J Rhynchopus Diplonemida Diplonema

  10. Jaderný dimorfismus nálevníků

  11. Zrání makronukleu

  12. Epigenetická dědičnost Tetrahymena: Mochizuki & Gorovsky, 2004 Oxytricha: Nowacki et al., Nature 2008

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