Steps and Timeline

1. Steps and Timeline Professor Hanne Tønnesen MD PHD &  Nermin Ghith, MPH, PHD Student Shu-Ti Chiou MD PHD MSc Oliver Groene MSc PHD

2. Trial Profile Clin Dept n = 2x44 Intervention Data collect Control TAU R RP RP Intervention Data collect Control Data collect 1y 2y Site Visit & Data Val Control Data collect Site Visit & Data Val

3. Steps Inclusion: Agreement and Allocation Baseline Package Data Collection: Internal Audit + Q Plan Returning baseline Implementation of Q-plan Follow-up Package Data Collection; Int Audit + Rev Q-Plan Data Validation: Site Visit Certificate with results

4. 2011 2012 2013 2014 mo III IV I II III IV I II III IV I II III Inclusion, Agree, Allocate 1 Baseline Package 1 Int Audit + Q-Plan 2 Returning Package 1 Implementation 12 Follow-up Package - Int Audit + RevQ- Plan 2 + Site Visit certificate 2 Intervention Group: Time-line

5. 2011 2012 2013 2014 mo III IV I II III IV I II III IV I II III Inclusion, Agree, Allocate 1 Baseline Package 1 Int Audit + Q Plan 2 Returning Package 1 Implementation 12 Follow-up Package - Int Audit + Revised Quality Plan 2 Site Visit + certificate 2 Control Group: Time-line

6. 2011 2012 2013 2014 mo III IV I II III IV I II III IV I II III Incl, Agree, Allocate 1 Baseline Package 1 Int Audit + Q Plan 2 Returning Package 1 Implementation 12 Follow-up Package - Int Audit + Revised Quality Plan 2 Site Visit + certificate 2 Whole project time-line

7. We look forward to welcoming you onboard & to a fruitful collaboration!