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Optimizing Crohn's Disease Management: Strategies for Improved Patient Outcomes

Explore expert perspectives on patient heterogeneity, early treatment interventions, and personalized management approaches in Crohn's Disease. Learn about the benefits of tight monitoring, treatment goals, and novel therapies for better long-term clinical outcomes.

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Optimizing Crohn's Disease Management: Strategies for Improved Patient Outcomes

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Presentation Transcript

  1. Advances in Management Strategies for Crohn Disease

  2. Introduction

  3. Patient Heterogeneity in CD

  4. Discordance Between Symptoms and Mucosal Healing in CD

  5. Window of Opportunity in CD

  6. Comprehensive Management Approach to the IBD Patient – Expert Perspective

  7. Targets for CD Patient Management

  8. Earlier Biologic Treatment Is Associated With Better Remission Outcomes

  9. Shorter Disease Duration Is Associated With Higher Rates of Response to Vedolizumab

  10. Early Anti-TNF and IMM Therapy Is Associated With Better Long-Term Clinical Outcomes in CD

  11. Early anti-TNF Therapy Could Prevent Digestive Damage in CD

  12. Benefits of Tight Monitoring and Treat to Target Approach — CALM

  13. Real Life Challenges

  14. Tools for Early Patient Profiling in CD: Prognostic Factors for Disease Progression

  15. Tools for Early Patient Profiling in CD

  16. Individualized Predictive Markers for Severe CD

  17. Patient Case DiscussionCase 1

  18. Case 1 Initial Clinical Presentation

  19. Case 1 Initial Clinical Presentation (cont)

  20. Case 1Treatment of First CD Flare

  21. Case 1: How Did You Assess Risk for Disease Progression in This Patient?

  22. Case 1How Did You Set Your Treatment Goal?

  23. Case 1: Which Parameters Did You Consider to Make a Treatment Choice?

  24. Case 1: Which Treatment Would You Use in This Specific Patient?

  25. Case 1: How Do You Discuss Treatment Options With the Patient?

  26. Case 1: Which Criteria Do You Use to Make a Choice Between Treatments?

  27. Anti-TNF and Mucosal Healing in CD

  28. Vedolizumab and Mucosal Healing in CD

  29. Vedolizumab Safety Profile in CD

  30. Ustekinumab and Mucosal Healing in CD

  31. Treatment Choice Expert Perspective

  32. Patient Case DiscussionCase 2

  33. Case 2 Initial Clinical Presentation

  34. Case 2Treatment

  35. Case 2: How Did You Assess Risk for Disease Progression in This Patient?

  36. Case 2: What Triggered the Step-Up Approach in This Patient?

  37. Case 2: Which Criteria Do You Use to Make a Choice Between Treatments?

  38. Case 2: Which Criteria Do You Use to Make a Choice Between Treatments? (cont)

  39. Key Components of Successful Treatment in CD

  40. Abbreviations

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