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Cellular Reproduction. Cell division - A process in which a cell divides into 2 or more cells. Functions of cell division: *reproduction *growth and development *repair. Cellular Reproduction. In asexual reproduction :
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Cellular Reproduction Cell division - A process in which a cell divides into 2 or more cells. Functions of cell division: *reproduction *growth and development *repair
Cellular Reproduction • In asexual reproduction: • Single-celled organisms reproduce by simple cell division • There is no fertilization of an egg by a sperm FUNCTIONS OF CELL DIVISION Asexual Reproduction LM Sea stars African Violet Amoeba
Cellular Reproduction • Sexual reproduction requires fertilization of an egg by a sperm using a special type of cell division called meiosis.
Eukaryotic Chromosomes LM Chromosomes
Eukaryotic Chromosomes DNA double helix Histones • The DNA in a cell is packed into an elaborate, multilevel system of coiling and folding. • Histones are proteins used to package DNA in eukaryotes. • Nucleosomes consist of DNA wound around histone molecules. “Beads on a string” TEM Nucleosome Tight helical fiber Looped domains Duplicated chromosomes (sister chromatids) TEM Centromere
Chromosome Structure ●Chromosome unduplicated vs. duplicated ●Centromere ● Sister Chromatids
The Cell Cycle S phase (DNA synthesis; chromosome duplication) • The cell cycle consists of two distinct phases • Interphase • Mitotic phase Interphase (90% of time) G1 G2 Mitotic phase (M) (10% of time) Mitosis Cytokinesis
Interphase INTERPHASE Centrosomes (with centriole pairs) Interphase Chromatin • G1: Metabolism and growth • End of G1: Cell signaled to divide • S (synthesis): DNA is duplicated • G2: Cell forms chromosomes, completes preparations for cell and nuclear division Nuclear envelope Plasma membrane LM
Prophase and Prometaphase PROPHASE Fragments of nuclear envelope Early mitotic spindle Centrosome Centromere Chromosome, consisting of two sister chromatids Spindle microtubules
Metaphase, Anaphase, Telophase METAPHASE ANAPHASE TELOPHASE Nuclear envelope forming Cleavage furrow Daughter chromosomes Spindle
Cytokinesis Animal cells Plant cells
Meiosis • Sexual reproduction requires fertilization of an egg by a sperm using a special type of cell division called meiosis.
Meiosis Homologous chromosomes separate. Chromosomes duplicate. Sister chromatids separate. Duplicated pair of homologous chromosomes Pair of homologous chromosomes in diploid parent cell Sister chromatids MEIOSIS II MEIOSIS I INTERPHASE BEFORE MEIOSIS
Meiosis MEIOSIS I: INTERPHASE PROPHASE I METAPHASE I ANAPHASE I Microtubules attached to chromosome Sister chromatids remain attached Centrosomes (with centriole pairs) Sites of crossing over Spindle Sister chromatids Nuclear envelope Centromere Pair of homologous chromosomes Chromatin Homologous chromosomes pair up and exchange segments. Pairs of homologous chromosomes split up. Pairs of homologous chromosomes line up. Chromosomes duplicate.
Meiosis MEIOSIS II: SISTER CHROMATIDS SEPARATE TELOPHASE II AND CYTOKINESIS TELOPHASE I AND CYTOKINESIS PROPHASE II METAPHASE II ANAPHASE II Cleavage furrow Sister chromatids separate Haploid daughter cells forming Two haploid cells form; chromosomes are still doubled. During another round of cell division, the sister chromatids finally separate; four haploid daughter cells result, containing single chromosomes.
Meiosis Cross over: How do we account for genetic variation? *Independent assortment *Crossing over *Random fertilization Independent Assortment: