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IL-22. 20. 18. 100. 16. 90. 14. 80. 12. 70. 10. 60. 8. 50. 6. 40. 4. 30. 2. 20. 0. 10. 0. a. IL-22. IL-17A. IL-17F. mRNA level to HPRT (x10 -3 ). 200. 20000. 70000. 150. 15000. 50000. 100. 10000. 30000. 50. 5000. 10000. 0. 0. 0. 0. 1. 1. 100. 100.
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IL-22 20 18 100 16 90 14 80 12 70 10 60 8 50 6 40 4 30 2 20 0 10 0 a IL-22 IL-17A IL-17F mRNA level to HPRT (x10-3) 200 20000 70000 150 15000 50000 100 10000 30000 50 5000 10000 0 0 0 0 1 1 100 100 500 500 0 0.5 0.5 10 10 100 1 500 0.5 10 FICZ (nM) b c IL-17A IL-22 IL-17A IL-17F 2 50 70 40 % positive cells 1.5 60 30 1 % of positive cells 50 20 0.5 40 10 30 0 0 ctrl ctrl 1.0 mM bNF 0.5 mM bNF 1.0 mM bNF 0.5 mM bNF 0.1 mM bNF 0.1 mM bNF 20 10 0 +FICZ +FICZ +FICZ Suppl Figure 2