Biotechnology in Germany From BioRegions to BioClusters Keys for succes Dr. Klaus Plate CEO

1. Biotechnology in Germany From BioRegions to BioClusters Keys for succes Dr. Klaus Plate CEO Heidelberg Technology Park Sino-European Forum on Innovation Clusters Paris, January 25, 2007

2. Germany UK France Sweden Switzerland Netherlands Finland Belgium Denmark Italy big (150 and more employees) others medium (50 to 149 employees) small (1 to 49 employees) Norway Start-Up (up to 2 years) Spain Ireland 0 50 100 150 200 250 300 Source: Ernst & Young number of companies Biotechnologyin Europe

3. German BioRegions Bioinitiative Nord (Hamburg- Kiel-Lübeck BioRegio Greifswald-Rostock Region Bremen Region Nordwestl. Nieder- sachsen BioTOP Berlin-Bran- denburg BioRegio N Braunschweig- Hannover- Göttingen) BioRegio Rheinland (Köln-Bonn- Aachen BioMIT Mittelhessen (Marburg- Gießen) BioRegion Halle-Leipzig BioRegio Jena BioRegion Rhein-Main (Frankfurt-Mainz) BioRegio Regensburg BioRegion Rhein-Neckar- Dreieck BioRegio Stuttgart/ Neckar-Alb (Tübingen) Biotech- nologie Ulm Biotech- nologie München BioRegio Freiburg

4. German BioRegions Bioinitiative Nord (Hamburg- Kiel-Lübeck BioRegio Greifswald-Rostock Region Bremen Region Nordwestl. Nieder- sachsen BioTOP Berlin-Bran- denburg BioRegio N Braunschweig- Hannover- Göttingen) BioRegio Rheinland (Köln-Bonn- Aachen BioMIT Mittelhessen (Marburg- Gießen) BioRegion Halle-Leipzig BioRegio Jena BioRegion Rhein-Main (Frankfurt-Mainz) BioRegio Regensburg BioRegion Rhein-Neckar- Dreieck BioRegio Stuttgart/ Neckar-Alb (Tübingen) Biotech- nologie Ulm Biotech- nologie München BioRegio Freiburg

5. BioRegio Funding 50 million DM for research projects in biotechnology for three model regions: BioRegio Rhineland (Köln, Bonn, Achen) BioRegion Rhine-Neckar-Triangle (Heidelberg) Biotechnology Munich (München) plus 20 million DM for the special region: BioRegio Jena Source: BioRegion Rhine-Neckar-Triangle

6. Conditions for BioRegio Funding The perspective of a short or medium-term commercialisation of the results, preferentially by founding a biotech company The commercial realization of the results within the region The confinancing of the project by private capital, generally with at least 50 % of the total cost of the project Time span: 1st Jan 1997 – 31st Dec 2001 Source: BioRegion Rhine-Neckar-Triangle

7. Selecting projects for BioRegio Funding I.Criteria Scientific Quality Competitiveness (patent situation) Creation of Jobs Focus on regional strength Source: BioRegion Rhine-Neckar-Triangle

8. Since the launch of the BioRegio Contest in 1997: • 55 new biotech companies in the Heidelberg BioCluster • 45 research-driven companies in molecular biotechnology • 1.800 jobs created directly in biotech companies • 1.500 jobs in research-driven biotech companies • 8.000 jobs in the industry and 6.000 jobs in research institutions are dependent on biotechnology Source: BioRegion Rhine-Neckar-Triangle

9. German BioClusters Bioinitiative Nord (Hamburg- Kiel-Lübeck BioRegio Greifswald-Rostock Region Bremen Region Nordwestl. Nieder- sachsen BioTOP Berlin-Bran- denburg BioRegio N Braunschweig- Hannover- Göttingen) BioRegio Rheinland (Köln-Bonn- Aachen BioMIT Mittelhessen (Marburg- Gießen) BioRegion Halle-Leipzig BioRegio Jena BioRegion Rhein-Main (Frankfurt-Mainz) BioRegio Regensburg BioRegion Rhein-Neckar- Dreieck BioRegio Stuttgart/ Neckar-Alb (Tübingen) Biotech- nologie Ulm Biotech- nologie München BioRegio Freiburg

10. BioClusters BioClusters Keys for success

11. BioClusters Science Base • Universities • Research Institutes

12. BioClusters Company Base • Big Companies • Medium-sized companies • Start-ups

13. BioClusters Financial Base Availability of „smart“ equity and debt-finance • Seed money • Venture money

14. BioClusters Human Resources Availability of skilled workforce • Scientists • Business Professionals • Technicians • Post-docs

15. BioClusters Additional critical factos for success • Easy to reach by air, car, railway • Quality of life

16. BioClusters BioParks The drivers of BioClusters The right environment to start and grow biotech companies

17. BioClusters The Heidelberg Technology Park is a BioPark Center of the Heidelberg BioCluster

18. Heidelberg BioClusterHeidelberg Technology Park Profile • 500.000 sqft lab and office space • 75 tenant companies • 1.300 employees, 1.500 expected • 200 Associated Members

19. Heidelberg BioCluster Heidelberg Technology Park The Heidelberg Technology Park is an international Life Science Park, Center of the Heidelberg BioCluster. The Park is closely related to the Heidelberg University and to the worldfamous research institutes located here.

20. Heidelberg BioClusterHeidelberg Technology Park Technology Park Services Helping with • renting office and lab space • financing • managment • marketing • legal affairs

21. Heidelberg BioClusterHeidelberg Technology Park Technology Park Services (examples) • conference service • seminars, workshops • market place for machines, lab material, services, jobs • online and print platforms to communicate • organizing meetings • conference center • restaurant • Kindergarten • parking

22. Heidelberg BioClusterHeidelberg Technology Park Technology Park Networking Regional, national, international • developing a regional BiotechCommunity • working with national and international associations • creating strategic alliances and partnerships

23. TP Sisterpark Network Heidelberg BioCluster Heidelberg Technology Park Sisterpark Network 22 Partners in America, Asia, Europe A worldwide alliance to explore international markets and to offer information, collaboration and partnering.

24. Heidelberg Technology Park Sisterpark Network

25. Heidelberg BioCluster Heidelberg Technology Park CEBR: Council of European BioRegions  Uppsala  Tallinn Cambridge Oxford    Berlin Flanders  Heidelberg Paris   Munich Basel Lyon   Barcelona

26. Council of European BioRegions CEBR 'Building a competitive European biotechnology sector on the world stage’

27. CEBR – the need….an observation on European biotech Hundreds of small companies across Europe • A need to work together for best result in competitive world market • Diverse sources of assistance – not always apparent/easily accessible Founded on excellent science but must operate effectively to succeed 'Building a competitive European biotechnology sector on the world stage’

28. CEBR – the history Small group with common interest: Improving practical support for their biocommunities Creating network with appropriate/best point of contact in every biocommunity Promoting European biotechnology Network outline developed Funding achieved 'Building a competitive European biotechnology sector on the world stage’

29. CEBR – what it can offer • Operational support – companies should succeed on science, not fail on business practice • Europe-wide biotechnology network – rapid access to biotechs • Promotion of European biotechnology on world stage • Signposts to what works well 'Building a competitive European biotechnology sector on the world stage’

30. CEBR – what it does…. The ‘golden rules’ • ‘Bottom up’ – driven by biotech’s practical needs • Activities with direct benefit to biotechs • Working network – proactive members • Co-operation: co-operate to compete 'Building a competitive European biotechnology sector on the world stage’

31. TP Contact Heidelberg BioCluster Heidelberg Technology Park Contact: Dr. Klaus Plate, CEOTechnologiepark Heidelberg GmbHMarktplatz 10, 69117 Heidelberg, GermanyPhone: +49 6221 58-20500Fax: +49 6221 58-20990E-mail: klaus.plate@heidelberg.de technologiepark@heidelberg.deWeb: www.technologiepark-heidelberg.de

32. Thank you for your attention.