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Hosseinpour S, Mirmiran P, hosseinpanah F, Azizi F

Relation between dietary macronutrient and fiber intake with metabolic syndrome in Tehranian adults: Tehran Lipid and Glucose Study. Hosseinpour S, Mirmiran P, hosseinpanah F, Azizi F. Obesity research center, Research Institute for Endocrine Science,

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Hosseinpour S, Mirmiran P, hosseinpanah F, Azizi F

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  1. Relationbetween dietary macronutrient and fiber intake with metabolic syndrome in Tehranian adults: Tehran Lipid and Glucose Study Hosseinpour S, Mirmiran P, hosseinpanah F, Azizi F Obesity research center, Research Institute for Endocrine Science, SahidBeheshti University of Medical Sciences

  2. introduction Adult treatment panel (ATP) III guidelines • Highserum triglyceride levels (TG≥150 mg/dl) • Low HDL-C (<40 mg/dl for men and <50 mg/dl for women) • Elevated blood pressure ( ≥130 and/or ≥85 mm Hg) • Abnormal glucose hemeostasis (FBG ≥100 mg/dl) • Abdominal obesity American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement Criteria of abdominal obesity were specified by nationality or ethnicity on best available population estimate *In men ≥89 cm In women ≥91 cm Grundy et al. Circulation 2005; 112 Delavari et al. Diabetes care 2009; 32: 1092

  3. introduction(con`s)MetSIncreased risk of developing: • Diabetes • Cardiovascular Disease • Chronic kidney Diesease • Cancer (breast, colorectal) • Stroke and cerebrovascularedisease(in Asia) Prevalence of MetS • In representative sample in Tehran 42% in women 24% in men • In nationwide study in 30 province 35.6% Three years follow-up 2% Metabolic syndrome is growing into a significant public health problem Azizi et al. Diabetes Res ClinPract 2003; 61 Delavari et al. Diabetes Care 2009; 32

  4. introduction(con`s) Attributable factor Metabolic syndrome Feldeisen et al. ApplPhysiolNutrMetab 2007; 32 Galisteo et al. J NutrBiochem 2008; 19

  5. objective Examines the cross-sectional associations between macronutrients and fiber intake With metabolic syndrome in Tehranian adults.

  6. Materials and methodsstudy design and sample

  7. Materials and methods(cont’)Assessment of criteria • Dietary intake FFQ (valid and reliable) • Anthropometric Weight, Height, Waist, Hip, BMI, WHR • Biochemical assessment FBG TG HDL-C • Medical history

  8. Materials and methods(cont’)Statistical analysis Characteristic of participants were compared by sex using t test, and chi-square. logestic regression was used to study associations among quartile of macronutrient and fiber intakes with MetS, adjusted for age, smoking, energy intake and druge use, BMI and WHR. Odds Ratio of developing MetS were evaluate across quartile of macronutrients and fiber.

  9. results

  10. * Significantly different from male, P<0.05

  11. *Significantly different from male, P<0.05. § P=0.07

  12. *significantly different from metabolic syndrome, P<0.05

  13. *Significantly different from male, P<0.05. § P=0.07

  14. Model I: crude model Model II: BMI, WHR Model III: Model II + :adjusted for age, physical activity, total energy intake, smoking, drug use

  15. Model I: crude model Model II :adjusted for age, physical activity, total energy intake, smoking, drug use Model III: Model II + BMI, WHR Model I: crude model Model II: BMI, WHR Model III: Model II + :adjusted for age, physical activity, total energy intake, smoking, drug use

  16. conclusion InTehranian population, macronutrients and fiber intake is not associated with metabolic syndrome.

  17. Tank you for Your attention

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