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Inflammation and Course Themes

Inflammation and Course Themes. Nancy Long Sieber, Ph.D. Sept. 12, 2011. Life Expectancy of Americans at Various Ages in 1900-’02 and 2003 By Age, Gender and Race. Source : US CDC. Challenges and Adaptation. http://www.usc.edu/hsc/dental/PTHL312abc/312a/02/Graphics/figure01.gif.

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Inflammation and Course Themes

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  1. Inflammation and Course Themes Nancy Long Sieber, Ph.D. Sept. 12, 2011

  2. Life Expectancy of Americans at Various Ages in 1900-’02 and 2003By Age, Gender and Race Source : US CDC

  3. Challenges and Adaptation http://www.usc.edu/hsc/dental/PTHL312abc/312a/02/Graphics/figure01.gif

  4. http://www.siumed.edu/~dking2/crr/images/CR007b.jpg

  5. What is the significance of injury and toxicity? • Tissues differ in their capacity for repair • Epithelial cells are continuously replaced • Nerve cells, in general, do not divide • Organs also differ in their “safety factors” • All organs have some amount of excess capacity • With aging and injury, the excess capacity is lost, and this may lead to loss of function

  6. http://www.wirednewyork.com/hotels/marriott_marquis/images/marriott_marquis_elevators.jpghttp://www.wirednewyork.com/hotels/marriott_marquis/images/marriott_marquis_elevators.jpg

  7. Elevator cable for passenger elevators has a safety factor of about 11 http://www.gkivdo.com/gkii/wire_3.jpg

  8. Necrosis and Apoptosis http://pubs.niaaa.nih.gov/publications/arh25-3/image01.gif

  9. Developing human hand before web apoptosis http://www.i-am-pregnant.com/img/day48-hand.gif

  10. Developing hand after web apoptosis http://www.grg.org/breakingnews2001.htm

  11. Modified from: http://www.chrononhotonthologos.com/inactive/strokedr/hbothera.htm

  12. Inflammation http://www.uic.edu/classes/bios/bios100/lecturesf04am/inflammation01a.jpg

  13. Inflammation Pro-inflammatory cytokines IL-1 IL-6 TNF Positive acute phase reactants: LIVER Haptoglobin C3 Fibrinogen Serum amyloid A C-reactive Protein

  14. http://www.euromeds.co.uk/allergy-treatment-information.htm Allergen binds to IgE, which links to mast cells, triggering release of histamine.

  15. http://www.easterncarolinaent.com/Allergy-Triggers-copy.jpg Common Allergens

  16. Autoimmune Disease http://www.mctd.eu/images/AutoimmuneDisorder.jpg

  17. Cancer http://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.html

  18. http://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlhttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.html

  19. Stress Responses

  20. Obesity Trends* Among U.S. AdultsBRFSS,1990, 2000, 2010 (*BMI 30, or about 30 lbs. overweight for 5’4” person) 2000 1990 2010 No Data <10% 10%–14% 15%–19% 20%–24% 25%–29% ≥30%

  21. http://www.cancer.gov/cancertopics/factsheet/Risk/obesity

  22. http://www.lipidsonline.org/slides/slide01.cfm?q=abdominal+fat&pg=1http://www.lipidsonline.org/slides/slide01.cfm?q=abdominal+fat&pg=1

  23. http://mednews.wustl.edu/tips/page/normal/8947.html

  24. The women in this study did not gain weight, but they did have an increase in abdominal fat http://www.lipidsonline.org/slides/slide01.cfm?q=abdominal+fat&dpg=10

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