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Cutaneous Manifestation of Cardiovascular Disease. Done by Mohammad Binhussein. Dermatologists may be the first physician to diagnose an underlying cardiovascular disease. skin findings in addition to general dermatologic signs suggestive of cardiovascular disease. Infective endocarditis
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Cutaneous Manifestation of Cardiovascular Disease Done by Mohammad Binhussein
Dermatologists may be the first physician to diagnose an underlying cardiovascular disease
skin findings inaddition to general dermatologic signs suggestive of cardiovasculardisease • Infective endocarditis • Acute rheumatic fever • Cholesterol embolization syndrome • Lipid disorders • Kawasaki disease • Pseudoxanthoma elasticum
Infective endocarditis Osler nodes
Infective endocarditis Janeway lesions
Risk Factor? heart valves degenerative valve disease prosthetic valves intravenous drug use recent cardiac or dental surgery mitral valve prolapse and rheumatic heart disease
Causative Organism? Usually caused by viridans streptococci & staphylococci
Acute rheumatic fever postinfectious sequela of a group A β-hemolytic streptococcal pharyngitis
Acute rheumatic fever Erythema marginatum
Cholesterol embolization syndrome Livedo reticularis
Describe? red or blue, mottled, netlike discoloration
Xanthelasma Lipid Disorder
soft yellow macules or plaques Describe?
Premature development may indicate familial hypercholesterolemia
genetic disorder ofconnective tissue affecting the skin, eyes, and cardiovascular
immune-mediated vasculitis mucocutaneous lymph node syndrome fever lasting 5 or more days without explanation combined with at least 4 of the 5 principal clinical features, as follows: (1) bilateral conjunctival injection, (2) oral mucous membrane changes, (3) peripheral extremity changes, (4) polymorphous rash, and (5) cervical lymphadenopathy
The lentigines are dark brown irregularly shaped macules ranging in size from pinpoint to 5 cm with involvement of the face, neck, and upper trunk
Cardiocutaneous lentiginosis syndrome and multiple lentigines syndrome, is an autosomal dominant disorder of variable penetrance stands for Lentigines, ECG changes, Ocular telorism, Pulmonary valve stenosis, Abnormal genitalia, Retardation of growth, and Deafness.