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DNA encodes messenger RNA. DNA = Information transcription mRNA = Message translation Protein sequence = Assembly folding Folded protein = Function. Ribosome. mRNA encodes proteins. DNA = Information transcription mRNA = Message
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DNA encodesmessenger RNA DNA = Information transcription mRNA = Message translation Protein sequence = Assembly folding Folded protein = Function
Ribosome mRNA encodes proteins DNA = Information transcription mRNA = Message translation Protein sequence = Assembly folding Folded protein = Function
Protein folding Folding intermediates of apomyoglobin DNA = Information transcription mRNA = Message translation Protein sequence = Assembly folding Folded protein = Function U = unfolded E = early intermediate I = intermediate N = native
Levels of Protein Structure: Secondary Structure • ordering along short stretches of the protein b-sheets a-helices
Levels of Protein Structure: Tertiary Structure • overall conformation of the protein chain • information contained in the protein’s sequence of residues is sufficient to dictate the specific 3-dimensional structure that the chain will adopt (“native state”)