XXIX Annual Conference

1. High-level Research and Education:Key-services for Developing an Industrial Biotech Cluster XXIX Annual Conference October 6th 2007 Palace Hotel, Bari Speakers: • Dr. M. Antonelli, MerckSerono S.A. (CH) • Ing. G. Risola, MerckSerono Bari (I)

2. Topics • Industry external factors expected to impact Pharma & Biotech businesses • Key factors for competitive advantage within local Health Care System • Can we look at Biotech models like Boston or Leman lake areas ? • How can the local Educational System “contribute” to deliver • What has to change? People’ Change • Conclusions MA & GR

3. Industry external factors expected to impact Pharma and Biotech Businesses • Fast growing number of molecules deriving from the learning of auto-immuno deseases, oncology, neurology, etc. • Exponential growth of recombinant Monoclonal Antibody technologies Science & Technology MA & GR

4. Industry external factors expected to impact Pharma and Biotech Businesses • Balance between spending of HealthCare System and necessity to reduce global spending • Growing Safety consciousness and requirements from Health Authorities • Increase of Life Expectancy Social & Economics MA & GR

5. The case of Boston Area MA & GR

6. The case of Leman Lake Area MA & GR

7. Key factors for competitive advantage within local Health Care System • Excellence in Medical science • Excellence in Scientific Schools and Universities • Dynamic & Diversified Industrial Business • Good infrastructure and logistic • Excellence in “Hosting System” • Industrial oriented University research • Attractive remuneration for professionals MA & GR

8. Pharma & Biotech do not need only Scientists !!! • Biotech and Pharma Manufacturing • Quality Management (QA & QC) including Regulatory affairs specialists • Supply Chain & Cold Chain Management • Process Development and Technology Transfer • Technology Workshops and Start-ups • Engineering, Maintenance & Validation • Planning and ERP specialists MA & GR

9. Pharma & Biotech do not need only Scientists !!! • Automation and IT • Human Resources Management including training and development • Process Improvement and Operational Excellence • Industrial Cost Accounting • Project Management • Environmental Compliance MA & GR

10. How can the local Educational System “contribute” to deliver? • A problem solved in a process, in a product, in a Plant is worth many Thesys or Doctoral work • Local Industry must be seen as Customer • One happy Customer may be a good reason to sacrify some “research” activity • Several happy Customers mean fertile environment, generating additional crativity and interdisciplinary applications of successful business cases • Technology transfer between University and Industry MA & GR

11. How can the local Educational System “contribute” to deliver? Sharing knowledge, experiences & good practices is challenging but is a winning exercise !!! MA & GR

12. How can the local Educational System “contribute” to deliver? • More students sent to Industry for graduation work • Incentives to Industries or Organisation hiring former “students” • Intercompany Schools Sponsored by Universities, local Government, Region, Province, Industrial Associations and Industry: WHY ? to deliver specific Job Specialists, which training is not foreseen in targeted schools or University curricula, with trainers coming from both Academy and Industry MA & GR

13. How can the local Educational System “contribute” to deliver ? Such schools deliver specialists that can find a job locally or in other area and are provided with recognised certification at national level MA & GR

14. Define Topics With experts from Health Care Develop and Customise Questionnaire Define new Market needs Conduct final Assessment with industries HC institutions Assess Define Job families Review Results Design & Implement Methodology, Start Assessment Identify Educational gaps Select best Business cases Deploy Strategy, Link Concept to KPIs Implement Projects & Share Implement Set Targets Review with Potentia Final customers Projects at Clients Analyse & Share, Design Projects Set Targets for Job fulfilment Training on The job Share w/other schools Fine tune Training for Higher success rate Share Best Practice Define Potential for improvement Analyse Gaps Proposed Virtuous circle in educational excellence MA & GR

15. How can the local Educational System “contribute” to deliver ? Expectation of the “CLIENTS” • To have local resources to be immediately employed, reducing time and cost of training on the job Expectation of “USERS” • To find after school an alternative to University Studies that qualify for “focused” studies aimed to high specialisation • The OFFER must increase, the Quality of the offer must excell • And the measure of the quality is a simple bottom line indicator: % of users finding a job within 18 month MA & GR

16. What has to change? • We cannot leave all the responsibility of our future to the Institutions • We cannot expect an arid soil to get fertile after a single rain • We need to be “original”, by re-inventing what others do well somewhere else and sustain initiatives aimed to qualification of skills needed NOT ONLY to large industries. • It is time our local small industry enjoys top quality workers, technicians, managers to astonish and to attract more investments from somewhere else People change MA & GR

17. Conclusions We are sure there is nothing really new in what it has been said BUT • It is time that people “take a course” and not “get a course” • It is time that we ALL have to contribute to sustain this initiative and be extremely demanding MA & GR

18. Thanks for your kind attention See you next time in Bari MA & GR