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NADPH OXIDASE ACTIVATION

NADPH OXIDASE ACTIVATION. O 2. Cl -. O 2-. HOCl -. CELL MEMBRANE. 2H +. H 2 O 2. Cell activation. gp91 phox. gp91 phox. p22 phox. p22 phox. rap1. 2H +. Proton channel. rap1. rap1. p40 phox. p40 phox. GDI. GTP. rac. rac. GDP. p67 phox. p67 phox. NADPH. NADP + + 2H +.

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NADPH OXIDASE ACTIVATION

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  1. NADPH OXIDASE ACTIVATION O2 Cl- O2- HOCl- CELL MEMBRANE 2H+ H2O2 Cell activation gp91 phox gp91 phox p22 phox p22 phox rap1 2H+ Proton channel rap1 rap1 p40 phox p40 phox GDI GTP rac rac GDP p67 phox p67 phox NADPH NADP+ + 2H+ p47 phox p47 phox CYTOSOL

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