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Genealogy and DNA

Genealogy and DNA . Genetic Genealogy. Began around 2003 Growing availability of testing Growing affordability of testing Genographic Project Anthropological 2005 to 2010 Sponsored by IBM, National Geographic, Waitt Foundation Relies on DNA testing. DNA. DNA - Deoxyribonucleic acid

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Genealogy and DNA

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  1. Genealogy and DNA

  2. Genetic Genealogy • Began around 2003 • Growing availability of testing • Growing affordability of testing • Genographic Project • Anthropological • 2005 to 2010 • Sponsored by IBM, National Geographic, Waitt Foundation • Relies on DNA testing

  3. DNA • DNA - Deoxyribonucleic acid • Each cell in individual contains same DNA • Organized into chromosomes • Humans have 23 pairs • Contains genetic instructions • Genes • Over time DNA mutates

  4. DNA Testing Applications • Forensic • Paternity • Medical • Genealogical • Anthropological

  5. Cell Components

  6. Chromosomes

  7. DNA Types • Recombining (autosomal) • 22 chromosome pairs • Non-recombining • Sex determining chromosome (X Y) • Y is only passed from father to son • Mitrochrondial DNA • Passed from mother to offspring • Both male and female

  8. Both Types

  9. Recombining

  10. Non-recombining

  11. Types of Genealogical Tests • Paternal test • Uses yDNA • Only passes from father to son • as does surname • But other males with same surname should be the same • Uncle, brother, male cousins, etc • Maternal test • Uses mtDNA • Passes mother to children • Both sons and daughters

  12. Test Types (con’t) • Autosomal • Uses parts of 22 chromosomes • Can give racial makeup • % of European, African, Asian (Amerindian) • CODIS – FBI db – not used in genealogic • Can tell degree of relatedness between two persons for recent generations • Family Tree DNA, 23andMe, deCODEme

  13. DNA Testing Services • FamilyTreeDNA is largest • www.familytreedna.com • Test consists of cheek swab • Actual DNA testing is several weeks • Results • Generic haplogroup • Specific test results • Comparison to others results (ongoing) • Contact information of matches

  14. DNA Tests • yDNA (paternal) • 12, 37, 67, 111 marker tests • $99 - $339 • mtDNA (maternal) • HVR1, HVR2, Full Genome Sequence (FGS) tests • $99 – $299 • Family Finder (autosomal) - $289 • Several other tests

  15. How to Use Results • Haplogroup – genetic population • Remainder is meaningless without others • Collaborate • Make email available • Show EKA (Earliest Known Ancestor) • Share ancestors (GEDCOM) • Join surname project (yDNA only) • Enter data in ysearch.org and mitosearch.org • Actively try to pull lines together • Help achieve critical mass

  16. The Genographic Project • Anthropological DNA study • Study migration of groups • Based on DNA of isolated groups • Over past 60,000 years • Created haplogroups for both • yDNA • mtDNA

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