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Microscopic Anatomy of Skeletal Muscle

Microscopic Anatomy of Skeletal Muscle. Lab Week of February 25, 2008 Marieb & Mitchell: Exercise 14. Muscle Fibers. multinucleate nuclei in peripheral area myofibrils I and A bands myofilaments actin & myosin. Sarcomere. Z to Z M line in middle

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Microscopic Anatomy of Skeletal Muscle

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  1. Microscopic Anatomy of Skeletal Muscle Lab Week of February 25, 2008 Marieb & Mitchell: Exercise 14

  2. Muscle Fibers • multinucleate • nuclei in peripheral area • myofibrils • I and A bands • myofilaments • actin & myosin

  3. Sarcomere • Z to Z • M line in middle • thick and thin filaments overlap and interact to contract the myofibril

  4. SR, T tubules and Triads • At the junction of A and I, the sarcolemma indents to form the T tubule • Sarcoplasmic Reticulum (SR) like smooth ER in most cells • terminal cisternae: SR next to T tubules • Triads (terminal cisternae – T tubule – terminal cisternae)

  5. Fiber to Muscle Organization • muscle fiber • endomysium • perimysium • fascicle • epimysium • skeletal muscle • deep fascia • tendons or aponeuroses

  6. Activity 1 • Model of Muscle Cell • Look at fresh chicken muscle under microscope • Look at slide with cross section of skeletal muscle and locate the structures in Fig 14.4 (if visible) Activity 2

  7. The Neuromuscular Junction • axon • axon terminal • motor unit • 1 neuron and all the muscles it stimulates • Plate 4, pg 693

  8. Activity 3 • Model of skeletal muscle cell with NMJ? • Slide with motor unit • axon fibers • axon terminal • COMPARE WITH PLATE 4 on pg 693

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