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Sham

A. L. L. Elastin degradation score. 4. 3. 2. L. L. 1. 0. Sham. P. rTM. B. L. L. SMC content score. 4. 3. 2. 1. L. L. 0. Sham. P. rTM.

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Sham

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  1. A L L Elastin degradation score 4 3 2 L L 1 0 Sham P rTM B L L SMC content score 4 3 2 1 L L 0 Sham P rTM SUPPLEMENTARY FIGURE 5. Treatment with rTMD123 preserves elastin integrity and SMCs in the aortic wall 28 days after AAA induction. A, medial elastin degradation (n=6). Elastin degradation grading scales (4 grades) by VVG staining are indicated in right panels (Blue arrows indicating disrupted elastic lamella). B, SMC content (n=6). SMC content grading scales (4 grades) by α-SMA staining are indicated in right panels. (P=AAA-PBS, rTM=AAA-rTM. **P<0.01, ***P<0.001 compared with sham. #P<0.05 compared with AAA-PBS. L indicates lumen. All scale bars represent 50 μm.)

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