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DNA Structure & Photo 51 | Review Chapter 9 Quiz | Check Grade Sheets

Learn about the historical discoveries surrounding DNA, including Rosalind Franklin's X-ray diffraction and Watson and Crick's double helix model. Explore DNA replication and participate in the lab activity "Doublin' DNA".

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DNA Structure & Photo 51 | Review Chapter 9 Quiz | Check Grade Sheets

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  1. Hand in W.S. Tuning in to radioisotopes Check Grade Sheets Review Chapter 9 Quiz 1 Review DNA structure & Photo 51 Notes – Chapter 9 "No one can make you feel inferior without your consent." Eleanor Roosevelt To learn about the historical discoveries surrounding the genetic material, DNA. Title: Biology 3/14/07 Class Topics Objectives: Thursday, January 2, 20208:00 AM

  2. Class Assignments What By When • W.S. Tuning in to Radioisotopes 3/14/07 • Read 194-200 3/14/07 • W.S. 9.2 3/16/07 • Doublin’ DNA 3/16/07 • Due this class period • Due next class period • Due in the future

  3. Grade Sheet 2A – p. 157 (5 pts.)

  4. Rosalind Franklin • 1951 - X-ray diffraction • Maurice Wilkins • Suggested that DNA was two strands • Tightly coiled helix • Photo 51, flash

  5. From: http://www.pbs.org/wgbh/nova/photo51/pict-01.html

  6. Watson and Crick • James Watson (American) and Francis Crick (British) discovered the shape and organization of DNA • Double helix • two strands • sugar/phosphate backbone • nitrogenous bases in middle • Won Nobel Prize for DNA model • with Maurice Wilkins

  7. Replication(PBS) • DNA double helix (like a spiral staircase) is easily replicated (doubled) • Occurs during S phase of cell cycle • 1. Enzyme, DNA helicase, attaches to DNA molecule • Hydrogen bonds between strands break (DNA unzips and unwinds) • Forms replication forks • Areas where the strands separate

  8. Replication (DNAi) • 2. DNA polymerase bonds free nucleotides (floating in nucleus) to exposed nitrogen bases • adenine to thymine & guanine to cytosine • 3. Hydrogen bonds formed between nitrogen bases • Proofreading • DNA polymerase can go back and check for errors • 1 error per 1 billion nucleotides

  9. Lab – Doublin’ DNA • Procedure 1 and 2 – cut out the nucleotides • 3. Use the DNA strand • GTCAACTG • 4. Have work checked after #4 • Pick up your homework W.S. when done.

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