1 / 246

HEART TRANSPLANTATION

Comprehensive analysis slides on adult heart transplant recipient characteristics, diagnosis, retransplants, and indications. Data presented by location, era, age group, and retransplant intervals.

jonathanmiller
Download Presentation

HEART TRANSPLANTATION

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. HEART TRANSPLANTATION Adult Recipients 2014 JHLT. 2014 Oct; 33(10): 996-1008

  2. Table of Contents • Donor and recipient characteristics: slides 3-53 • Immunosuppression: slides 54-71 • Survival slides: slides 72-140 • Morbidity: slides 141-169 • Multivariable analyses: slides 170-246 2014 JHLT. 2014 Oct; 33(10): 996-1008

  3. Donor and Recipient Characteristics: • Diagnosis and retransplant indications: slides 4-11 and 14 • Retransplants by year: slide 12 • Retransplants by inter-transplant interval: slides 13-15 • Recipient and donor characteristics: slides 16-49 2014 JHLT. 2014 Oct; 33(10): 996-1008

  4. Adult Heart TransplantsDiagnosis 2014 For some retransplants diagnosis other than retransplant was reported, so the total percentage of retransplants may be greater. JHLT. 2014 Oct; 33(10): 996-1008

  5. Adult Heart RetransplantsIndications 2014 JHLT. 2014 Oct; 33(10): 996-1008

  6. Adult Heart TransplantsDiagnosis by Location and Era Europe North America Other 2014 For some retransplants diagnosis other than retransplant is reported, so the total percentage of retransplants may be greater. JHLT. 2014 Oct; 33(10): 996-1008

  7. Adult Heart TransplantsDiagnosis by Location(Transplants: January 2006 – June 2013) 2014 For some retransplants diagnosis other than retransplant is reported, so the total percentage of retransplants may be greater. JHLT. 2014 Oct; 33(10): 996-1008

  8. Adult Heart RetransplantsIndications by Location(Retransplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  9. Adult Heart RetransplantsIndication by Diagnosis at Original Transplant(Retransplants: January 2006 – June 2013) 2014 For some retransplants diagnosis of retransplant is reported JHLT. 2014 Oct; 33(10): 996-1008

  10. Adult Heart TransplantsDiagnosis by Age Group(Transplants: January 2006 – June 2013) 2014 For some retransplants diagnosis other than retransplant is reported, so the total percentage of retransplants may be greater. JHLT. 2014 Oct; 33(10): 996-1008

  11. Adult Heart RetransplantsIndication by Age Group(Retransplants: January 2006 – June 2013) 2014 There were only 11 retransplants in 70+ years age group JHLT. 2014 Oct; 33(10): 996-1008

  12. Adult Heart Retransplantsby Year of Retransplant 2014 JHLT. 2014 Oct; 33(10): 996-1008

  13. Adult Heart Retransplantsby Inter-Transplant Interval (Retransplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  14. Adult Heart RetransplantsIndication by Inter-Transplant Interval (Retransplants: January 2006 – June 2013) 2014 For some retransplants diagnosis of retransplant is reported JHLT. 2014 Oct; 33(10): 996-1008

  15. Adult Heart RetransplantsRecipient Age by Inter-Transplant Interval (Retransplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  16. Adult Heart TransplantsDonor and Recipient Characteristics Continuous factors are expressed as median (5th-95th percentiles) 2014 1 Based on 4/1994-2000 transplants. JHLT. 2014 Oct; 33(10): 996-1008

  17. Adult Heart TransplantsDonor and Recipient Characteristics (Cont’d) Continuous factors are expressed as median (5th-95th percentiles) 2014 1 Based on 4/1994-2000 transplants. 2 Based on 7/2004-2005 transplants. JHLT. 2014 Oct; 33(10): 996-1008

  18. Adult Heart TransplantsDonor and Recipient Characteristics Continuous factors are expressed as median (5th-95th percentiles) (Cont’d) 1 PRA was collected as a single percentage outside of US. Until mid-2004 PRA was collected in US as a single percentage. After this date, PRA was collected separately for Class I and Class II. 2 Based on US 2001-6/2004 transplants and non US 2001 - 2005 transplants. 3 Based on non US transplants. 4 Based on US transplants. 5 Based on 4/1994-2000 transplants. 2014 JHLT. 2014 Oct; 33(10): 996-1008

  19. Adult Heart TransplantsDonor and Recipient Characteristics (Cont’d) 2014 For some retransplants diagnosis other than retransplant is reported, so the total percentage of retransplants may be greater. JHLT. 2014 Oct; 33(10): 996-1008

  20. Adult Heart TransplantsDonor and Recipient Characteristics 1 Based on 4/1994-2000 transplants. 2 Based on 11/1999-2000 transplants. 3 Based on 2005 transplants. 4 Based on 5/1995-2000 transplants. (Cont’d) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  21. Adult Heart RetransplantsDonor and Recipient Characteristics Continuous factors are expressed as median (5th-95th percentiles) 2014 1 Based on 4/1994-2000 retransplants. JHLT. 2014 Oct; 33(10): 996-1008

  22. Adult Heart RetransplantsDonor and Recipient Characteristics (Cont’d) Continuous factors are expressed as median (5th-95th percentiles) 2014 1 Based on 4/1994-2000 retransplants. JHLT. 2014 Oct; 33(10): 996-1008

  23. Adult Heart RetransplantsDonor and Recipient Characteristics (Cont’d) Continuous factors are expressed as median (5th-95th percentiles) 2014 1 Based on 4/1994-2000 retransplants. JHLT. 2014 Oct; 33(10): 996-1008

  24. Adult Heart RetransplantsDonor and Recipient Characteristics (Cont’d) 2014 For some retransplants diagnosis of retransplant is reported JHLT. 2014 Oct; 33(10): 996-1008

  25. Adult Heart RetransplantsDonor and Recipient Characteristics (Cont’d) 1 Based on 4/1994-2000 retransplants. 2 Based on 5/1995-2000 retransplants. 2014 JHLT. 2014 Oct; 33(10): 996-1008

  26. Adult Heart TransplantsDonor and Recipient Characteristics by Transplant Type(Transplants: January 2006 – June 2013) Continuous factors are expressed as median (5th-95th percentiles) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  27. Adult Heart TransplantsDonor and Recipient Characteristics by Transplant Type(Transplants: January 2006 – June 2013) 2014 (Cont’d) JHLT. 2014 Oct; 33(10): 996-1008

  28. Adult Heart TransplantsDonor and Recipient Characteristics by Transplant Type(Transplants: January 2006 – June 2013) (Cont’d) Continuous factors are expressed as median (5th-95th percentiles) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  29. Adult Heart TransplantsDonor and Recipient Characteristics by Transplant Type(Transplants: January 2006 – June 2013) 2014 (Cont’d) JHLT. 2014 Oct; 33(10): 996-1008

  30. Adult Heart TransplantsDonor and Recipient Age (Transplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  31. Adult Heart TransplantsDonor and Recipient Age(Transplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  32. Adult Heart TransplantsDonor and Recipient Age by Transplant Type (Transplants: January 2006 – June 2013) Primary Retransplant 2014 There were only 11 retransplants in 70+ years recipient age group JHLT. 2014 Oct; 33(10): 996-1008

  33. Adult Heart TransplantsDonor and Recipient Age by Transplant Type(Transplants: January 2006 – June 2013) 2014 There was only 1 retransplant in 0-10 years donor age group and 12 retransplants in donor 60+ age group JHLT. 2014 Oct; 33(10): 996-1008

  34. Adult Heart TransplantsDonor and Recipient Age (Transplants: January 2006 – June 2013) 2014 R2 = 0.01, p < 0.0001 JHLT. 2014 Oct; 33(10): 996-1008

  35. Adult Heart RetransplantsDonor and Recipient Age (Retransplants: January 2006 – June 2013) 2014 R2 = 0.04, p < 0.0001 JHLT. 2014 Oct; 33(10): 996-1008

  36. Adult Heart TransplantsRecipient Gender by Location (Transplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  37. Adult Heart TransplantsDonor Gender by Location (Transplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  38. Adult Heart TransplantsRecipient Gender by Transplant Type (Transplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  39. Adult Heart TransplantsDonor Gender by Transplant Type (Transplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  40. Adult Heart Transplantsby PRA Value by Transplant Type(Transplants: January 2006 – June 2013) If Class I and Class II values were reported separately, the greater of the two values was used. 2014 JHLT. 2014 Oct; 33(10): 996-1008

  41. Adult Heart Transplants% of Patients Bridged with Mechanical Circulatory Support* (Transplants: January 2000 – December 2012) 2014 * LVAD, RVAD, TAH, ECMO JHLT. 2014 Oct; 33(10): 996-1008

  42. Adult Heart Transplants% of Patients Bridged with Mechanical Circulatory Support* by Era and Transplant Type(Transplants: January 2000 – June 2013) 2014 * LVAD, RVAD, TAH, ECMO JHLT. 2014 Oct; 33(10): 996-1008

  43. Adult Heart Transplants% of Patients Bridged with Mechanical Circulatory Support* by Year and Device Type 2014 * LVAD, RVAD, TAH, ECMO JHLT. 2014 Oct; 33(10): 996-1008

  44. Adult Heart Transplants Number and % of Combined Organ Transplants Reported by Year and Type of Transplant 2014 JHLT. 2014 Oct; 33(10): 996-1008

  45. Adult Heart Transplants Number of Combined Organ Transplants Reported by Year and Type of Transplant 2014 For heart retransplant patients, all combined organ transplants were heart-kidney except for one heart-liver transplant performed in 2009. JHLT. 2014 Oct; 33(10): 996-1008

  46. Adult Heart TransplantsRecipient BMI Distribution by Location (Transplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  47. Adult Heart TransplantsRecipient BMI Distribution by Diagnosis (Transplants: January 2006 – June 2013) 2014 For some retransplants diagnosis other than retransplant was reported, so the total percentage of retransplants may be greater. JHLT. 2014 Oct; 33(10): 996-1008

  48. Adult Heart TransplantsRecipient Diabetes Mellitus Distribution by Location (Transplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

  49. Adult Heart TransplantsRecipient Diabetes Mellitus Distribution by Diagnosis (Transplants: January 2006 – June 2013) 2014 For some retransplants diagnosis other than retransplant was reported, so the total percentage of retransplants may be greater. JHLT. 2014 Oct; 33(10): 996-1008

  50. Adult Heart TransplantsRecipient Cigarette History by Location (Transplants: January 2006 – June 2013) 2014 JHLT. 2014 Oct; 33(10): 996-1008

More Related