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Molecular Level Investigation of Apatite Dissolution Seung-Wuk Lee, University of California-Berkeley, DMR 0747713. The primary goal of this project is to understand the molecular level surface characteristics of hydroxyapatite crystal as a bone model surface.

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Publications:

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  1. Molecular Level Investigation of Apatite DissolutionSeung-Wuk Lee, University of California-Berkeley, DMR 0747713 The primary goal of this project is to understand the molecular level surface characteristics of hydroxyapatite crystal as a bone model surface. We synthesized single crystal (100) hydroxyapatite (HAP) surfaces and investigated the novel features of surface during the dissolution processes using in situ atomic force microscopy techniques. We verified that the HAP exhibit the surface structure dependent dissolution patterns which is governed by the symmetry of the HAP crystals. During the dissolution processes, we verified the surface chemical composition and their dissolution properties depending on ionic concentration and surface defects. We achieved the following specific aims: 1-1. Synthesized (100) single crystal HAP surfaces. 1-2. Characterized microscopic dissolution properties of (100) HAP surfaces depending on ionic concentration, defect structures, surface structures. Synthesis of hydroxyapatite (100) surface and characterization using in situ atomic force microscopy techniques. Publications: 1.In situ Observation of Microscopic Dissolution of Defected Bone Mineral, Langmuir,2008,24, 11063-11066 2. The Effect of Salinity on Bone Mineral Dissolution Studied by Atomic Force Microscopy, Journal of Physical Chemistry C, 2009, 113, 3369-3372. 3. Kwon, K.-Y.; Wang, E.; Chung, A., Chang, N., Lee, S.-W. Characterization of the Dominant Molecular Step Orientations on Hydroxyapatite (100) Surfaces, Langmuir, 2009, 25 , 7205–7208

  2. “Finding Nano” Project impact to everywehere!! Seung-Wuk Lee, University of California-Berkeley, DMR 0747713 • Broad Impact: • Through the support of the NSF grant, we made the following efforts for the broad impact: • PI developed a class entitled” Introduction of Bionanoscience and Bionanotechnology. In this course, there is a student activity entitled “Finding Nano” which identifies the various examples of the bionanoscience in our daily life. • Lee lab also introduced NSF funded research to the parents and high school students in CAL Day event • A summer internship students (AJ) from UC Merced and participated in NSF funded internship program in 2009 (COINS). • An exchange student from France (Ecole Polytechnique, France) participated in the Lee Lab research. • One of our research in Finding Nano themes was covered by Technology Review in Feb, 2009. a b Please insert an image or group of images here to illustrate your broader impacts activities. If you need more space, you may reduce the adjacent textbox. Please use lettering that is clearly visible (i.e. not too small). Please include a brief figure caption. c d e f

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