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Cancun, December 7, 2011. GA2LEN WAO and Guidelines. Prof. Giorgio Walter Canonica Allergy and Respiratory Diseases Department University of Genoa. 1°vice President. Past President. Guyatt GH ACP J Club 1991 Mar-Apr. 20 years. From OBM to EBM. Bousquet J. et al.,Allergy 2004.
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Cancun, December 7, 2011 GA2LEN WAO and Guidelines Prof. Giorgio Walter Canonica Allergy and Respiratory Diseases Department University of Genoa 1°vice President Past President
Guyatt GH ACP J Club 1991 Mar-Apr 20 years Compalati 09
From OBM to EBM Bousquet J. et al.,Allergy 2004
Background Principles Procedures Graphics Quality Conclusions Shekelle BMJ 1999; 318; 593-596 Università degli Studi di Genova metanalysis E.B.M Opinion Based
ARIA Guidelines: Recommendationsfor Management of Allergic Rhinitis E.B.M Check for asthma Moderate/ severe persistent Mild persistent Moderate/ severe intermittent Mild intermittent Intranasal corticosteroid Local chromone Leukotriene receptor antagonists Second-generation nonsedating H1-antihistamine Intranasal decongestant (<10 days) or oral decongestant Allergen and irritant avoidance Consider immunotherapy Bousquet et al. J Allergy Clin Immunol. 2001;108(5 suppl):S147. At: http://www.whiar.org.
EAACI/GA2LEN/EDF Guidelines for Management of Urticaria Zuberbier et al. Allergy. 2006;61:321-331.
3rd International Consensus Meeting on Urticaria Urticaria 2008 EAACI / WAO / GA2LEN / EDF Guidelines
Management Zuberbier et al. Allergy. 2009; 64: 1427-1443.
Factors that influence the strength of a recommendation • Balance between desirable and undesirable effects • Quality of evidence • Patients’ values and preferences • Costs
Braido et al. Allergy 2010: DOI: 10.1111/j.1398-9995.2010.02383.x.
Thank You canonica@unige.it