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ADC Calculations

ADC Calculations. Lars Ewell Radiation Oncology University of Arizona Medical Center. 2/8/08. 1. ADC Across Slices. ADC needed for entire lesion, NOT for single contour. Area/Volume needs to be accounted for. Slice spacing also can affect values. Imaging Protocol: First Patient.

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ADC Calculations

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  1. ADC Calculations Lars Ewell Radiation Oncology University of Arizona Medical Center 2/8/08 1

  2. ADC Across Slices • ADC needed for entire lesion, NOT for single contour. • Area/Volume needs to be accounted for. • Slice spacing also can affect values.

  3. Imaging Protocol: First Patient • Given standard treatment for GBM(resected): 2Gy/Fx  23 Fx (46Gy) + 2Gy/Fx  17 Fx (14Gy). Tx finished on 2/19/07. Total of 60Gy. This Tx alone would have enabled enrollment in protocol. • Prescribed additional dose of 15 Gy to same area via Stereotactic Radio Surgery (SRS). Patient at high risk for radiation necrosis. Enrolled/scanned on 3/23/07. Scan time 1 hr 13min. • Treated with 15 Gy additional radiation on 3/28/07.

  4. MRI Scans Used for Contouring: T2 FLAIR (?) 1 2 3 4 5 6

  5. MRI Scans Used for ADC Calculation – diffrad, b=0 1 2 3 4 5 6

  6. Comparison of Scans • T2 FLAIR/Brainscan  Vlesion=9.14cc • b=0 Protocol Scan  Slice Thickness = 5mm • b=0 Protocol Scan  Slice Spacing = 7mm

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