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Treatment Strategies for Voice Disorders Associated with Larygopharyngeal Reflux (LPR). A Literature Review Kathleen Bell December 5, 2012. Introduction. Research of the Literature reveals confusion and controversy
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Treatment Strategies for Voice Disorders Associated with Larygopharyngeal Reflux (LPR) A Literature Review Kathleen Bell December 5, 2012
Introduction • Research of the Literature reveals confusion and controversy • “Interesting clinical paradox – Most underdiagnosed and overdiagnosed clinical entity in laryngology” (Bransky & Sulika)
STANDARD ANTIREFLUX THERAPY • Phase 1 A. Dietary modification B. Life-style modification C. Medications – antacids • Phase 2 A. H2 blockers B. Proton pump inhibitors C. Prokinetic agents • Phase 3 A. Double dose PPI B. Surgery (fundoplication)
Jamie Koufman pH water (8.8 & )
Dietary & Herbal Adjunctive Therapies - Melatonin - D-Limonene - Iberogast - Gluten Free Diet
PPI’s & Pharmaceuticals • Often double doses needed • Many patients unresponsive • Symptoms recurrent • Lifetime therapy • Prolonged use causes significant side-effects
Body Modalities • Chiropractic Care • Accupuncture
Voice Therapy & Psychological Therapy • Preventative Strategy • Component of comprehensive Therapeutic Strategy
Most Important Studies & Authors • Jamie Koufman (1991)– “The Otolaryngologic Manifestations of Gastroesophageal Reflux Disease.” • Belafsky et al (2002) – “Symptoms and Findings of Laryngopharyngeal Reflux.” • Johntson et al (2003) – “Cell Biology of Laryngeal Epithelial Defenses in Health and Disease.” • Kahn et al (2006) – “Laryngopharyngeal Reflux – A Literature Review.” • Sataloff et al (2006) – Reflux Laryngitis and Related Disorders • Bransky & Sulica (2009) – Classics in Voice and Laryngology • Patrick (2011) – “Gastroesophageal Reflux Disease (GERD): A Review of Conventional and Alternative Treatments.”
References – 50+!!! • Alcantara & Anderson (2008) • Amin et al (2001) • Aronson & Bless (2009) • Behlau & Oliveira (2009) • Belafsky et al (2001, 2002) • Boone et al (2010) • Bransky & Sulica (2009) • Cammarota et al (2003) • Chen, Xu, & Chen (2009) • Cuomo et al (2002) • Davies & Jahn (2004) • Dickman et al (2007). • Gainor et al (2011) • Halum et al (2005) • Hein, Tina (1999) • Hershcovici & Fass (2011) • Hopkins et al (2009). • Johnston et al (2003, 2004 ) • Kahn et al (2006) • Karkos et al (2007) • Kelchner et al (2005) • Koufman (2011) • Koufman &Johnston (2012) • Koufman et al (2002) • Koufman, Stern, & Bauer (2010) • Lloyd, Adam Thomas (2011) • McGuirt, William F. (2003) • Miskovitz & Betancourt (2005) • Mjönes et al (2005) • Møller & West (2000) • Moniniet al (2006) • Moss & Kelly (2007) • Murry et al (2006) • Nowak et al (2010) • Patrick, Lyn (2011) • Pitman (2010) • Rees & Belafsky (2008) • Ross et al (1998) • Sana et al (2011) • Sandage & Emerich (2002) • Sataloff, Robert T. (1991, 1998,2005, 2006,2010) • Sataloff et al (2006, 2012) • Sereg-Baharet al (2005) • Smoak & Koufman (2001) • Spencer (2006) • Syed & Bleach (2009) • Timmermans et al (2005) • Usai et al (2008) • Vashani et al (2010) • Watson et al (1997) • Wright et al (2005)
Images Used • Slide 1 – funnyjokes.org • Slide 3 – babychoicbariatrics.com • Slide 4 – epgpatientdirect.org • Slide 10 – refluxcookbook.com • Slide 13 – http://en.wikipedia.org • Slide 13 – www.bennettclinic.com/chiropractic.jpg • http://www.w3.org/TR/xhtml1/DTD/xhtml1-strict.dtd
Conclusions • Wealth of Research / Many Uncertainties • What is normal ? • Subtle changes = significant effects • Multidisciplinary team • Need for more specific controlled studies • Literature review integral to discovering what has been done, what needs to be done and whether or not you want to do it • Know the important publications: Journal of Singing, Journal of Voice, Laryngoscope, Otolaryngology, Head & Neck Surgery,