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Principles of Pharmacology The Pathophysiologic Basis of Drug Therapy

Explore the synthesis and modulation of progestins, androgens, and estrogens. Learn about the intracellular conversion processes, hormonal system functionalities, menstrual cycle, and pharmacological interventions. Discover tissue-specific actions and receptor binding structures.

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Principles of Pharmacology The Pathophysiologic Basis of Drug Therapy

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  1. Principles of PharmacologyThe Pathophysiologic Basis of Drug Therapy

  2. Chapter 29 Pharmacology of Reproduction

  3. Synthesis of Progestins, Androgens,and Estrogens • Figure 29-1

  4. Intracellular Conversion of Testosterone to Dihydrotestosterone • Figure 29-2

  5. The Hypothalamic-Pituitary–Reproduction Axis • Figure 29-3

  6. Two-Cell Systems for Gonadal Hormone Action • Figure 29-4

  7. The Menstrual Cycle • Figure 29-5

  8. Pharmacologic Modulation of Gonadal Hormone Action • Figure 29-6

  9. A Model for the Tissue Specificityof Action of SERMs • Figure 29-7

  10. Structural Comparison of Estrogen (Natural Ligand) and Raloxifene (SERM) Bound to the Estrogen Receptor • Figure 29-8

  11. Structure of Synthetic Estrogens • Figure 29-9

  12. Structure of Synthetic Progestins • Figure 29-10

  13. Structure of Progestins CommonlyUsed in Oral Contraceptives • Figure 29-11

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