Foundation Grants

1. Foundation Grants Where to Begin? May 1, 2014

2. So, You want a Foundation Grant? • Step 1: Call your development department • If you work in BMC space, call Kirsten Hinsdale, Director of Development at 617-414-5571 for guidance • If you work in BU space, call the Office of Sponsored Programs at 617-638-4600 for guidance Today, we will provide a brief overview of: • three of the largest foundations that fund basic science and healthcare research in the US: • American Cancer Society • American Diabetes Association • American Heart Association • How to repurpose your NIH grant for a foundation; positives and cautions to this strategy • Grant services provided by the BMC Development Office

3. AMERICAN CANCER SOCIETY • The Nation’s largest private funder of cancer research • 100 active grants in Massachusetts totaling $42,782,333, with three at BUMC (BMC/BU) • Funding is focused on peer-reviewed research but they also fund clinical research and training of health professionals • “ACS awards research grants and fellowships to promising early-career scientists with unique hypotheses for cancer prevention and study, fostering the next generation of cancer research…”

4. AMERICAN CANCER SOCIETY • Research Areas of Interest to ACS: • Biology • Etiology (causes of cancer) • Prevention • Early Detection, Diagnosis, and Prognosis • Treatment • Cancer Control, Survivorship, and Outcomes Research • Scientific Model Systems

5. AMERICAN CANCER SOCIETY GRANT TYPES: • New Initiatives and Requests for Applications • Research Grants for Independent Investigators • Mentored Research Grants • Health Professional Training Grants • Professor Grants • International Fellowships

6. AMERICAN CANCER SOCIETY Contact: www.cancer.org for more information and to identify if your research fits one of the open opportunities. Resources: • https://www.icrpartnership.org/index.cfm • http://www.aicr.org/ • http://www.avonfoundation.org/ • http://www.cancer.gov/ • http://www.komen.org

7. AMERICAN CANCER SOCIETY ACS Grant Programs: • Molecular Genetics and Biochemistry of Cancer • Cancer Cell Biology and Metastasis • Preclinical and Translational Cancer Research • Clinical Cancer Research and Immunology • Cancer Control and Prevention Research • Health Professional Training in Cancer Control

8. AMERICAN DIABETES ASSOCIATION • The Research Program accepts applications for research in all areas relevant to diabetes, from basic laboratory research to clinical and behavioral science • - See more at: http://www.diabetes.org/research-and-practice/we-are-research-leaders/how-grant-money-is-divided.html?loc=rp-slabnav#sthash.H3xVdyc3.dpuf

9. AMERICAN DIABETES ASSOCIATION

10. AMERICAN DIABETES ASSOCIATION • ADA Grant Programs:

11. AMERICAN DIABETES ASSOCIATION • Core Program • OverviewOur Core Program supports innovative basic, clinical and translational research projects across a broad spectrum of topics relevant to diabetes and its complications. The program offers grants for investigators at various career stages, including specific training and career development opportunities for early-career investigators as they advance their diabetes research careers. • NOTE: the upcoming call for applications (July 2014 deadline) has been delayed until October 2014. Updated grant mechanisms and application materials will be available online August 2014.

12. AMERICAN DIABETES ASSOCIATION Targeted RFA Program Overview: This category varies, with the most recent call for proposals being the ADA-ASP Young Investigator Career Development Award in Geriatric Endocrinology. It was a supplemental grant to the NIA GEMSTAR program, for people with this R03 grant only. The deadline for this was May 1st. Look for these periodically on the website or sign up to receive announcements at www.diabetes.org

13. AMERICAN DIABETES ASSOCIATION • Pathway Program Overview • Purpose: To accelerate the research needed to discover solutions and ultimately end this deadly epidemic, the Association has launched a bold new initiative, Pathway to Stop Diabetes. With a goal of funding 100 new diabetes investigators over the next decade, Pathway provides crucial support to researchers focusing on innovative ideas and transformational approaches.Pathway supports creative scientists who are just starting their careers in diabetes research, or who are already established in another field but want to expand their focus to diabetes research. Through individual awards of $1.6257 million • NOTE: • Only available by institutional nomination. • Currently accepting applications • Due Date July 1, 2014

14. AMERICAN DIABETES ASSOCIATION Resources: • NIH National Center for Biotechnology Information (NCBI)The NIH National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information.NIH Molecular Libraries ProgramThe Molecular Libraries Roadmap offers biomedical researchers access to the large-scale screening capacity, along with medicinal chemistry and informatics, necessary to identify chemical probes to study the functions of genes, cells, and biochemical pathways. This will lead to new ways to explore the functions of genes and signaling pathways in health and disease.Network for Pancreatic Organ Donors with Diabetes (nPOD)The Network for Pancreatic Organ Donors with Diabetes (nPOD) is a collaborative research project that supports diabetes investigators by providing, without cost, rare and difficult to obtain tissues from donors with type 1 and type 2 diabetes. Interested researchers are encouraged to apply to obtain nPOD tissues, or to request access to analyze cases in the nPOD Online Pathology site. 

15. AMERICAN DIABETES ASSOCIATION Resources: • T1D ExchangeA dynamic, multi-purpose, real-world patient data platform designed to accelerate all aspects of drug and device development. T1D Exchange has established a unique model to speed better treatments, therapies and research for type 1 diabetes (T1D).Team Science ToolkitDeveloped by the National Cancer Institute’s (NCI) Science of Team Science (SciTS) team, the Team Science Toolkit is an interactive website where visitors can freely upload/download publicly available resources that support the practice and study of team science. The Toolkit connects professionals from many disciplines, providing a forum for sharing ideas. • TrialNetA clinical trials network that conducts studies designed to evaluate new approaches to prevent or ameliorate Type 1 Diabetes. Researchers can submit proposals for clinical trial protocols, request biological samples through its Living Biobank initiative, or submit proposals for ancillary studies that complement the objectives of TrialNet studies.

16. AMERICAN HEART ASSOCIATION • The American Heart Association is committed to identifying and supporting specific science areas deemed critical to achieving our mission and strategic objectives. • Foundation and corporate support for strategically focused research, as well as partnerships with other professional organizations, allow the AHA to fund special initiatives or awards. • The American Heart Association funds investigator-initiated career development and knowledge discovery projects through its research programs. • Also funds specific science areas deemed critical to its mission and strategic objectives.  • The association has also established partnerships with various organizations to fund focused research programs.

17. AMERICAN HEART ASSOCIATION Grant Types: 1. Summer 2014 -- Scientist Development Grant Founders Affiliate (for New England)-  Due: July 25, 2014 Objective To support highly promising beginning scientists in their progress toward independence by encouraging and adequately funding research projects that can bridge the gap between completion of research training and readiness for successful competition as an independent investigator. Science Focus Research broadly related to cardiovascular function and disease and stroke, or to related clinical, basic science, bioengineering or biotechnology, and public health problems, including multidisciplinary efforts. Disciplines Proposals are encouraged from all basic, behavioral, epidemiological, and community and clinical investigations that bear on cardiovascular and stroke problems.

18. AMERICAN HEART ASSOCIATION Grant Types 2. Summer 2014 – Mentored Clinical and Population Research AwardFounders Affiliate – Due July 25, 2014 ObjectiveTo encourage early career investigators who have appropriate and supportive mentoring relationships to engage in high quality introductory and pilot clinical studies that will guide future strategies for reducing cardiovascular disease and stroke while fostering new research in clinical and translational science, and encouraging community- and population-based activities. This grant does not fund basic science or support senior researchers, but encourages mentoring of early career investigators.

19. AMERICAN HEART ASSOCIATION (cont’d.) Science FocusFunding is available for research related to cardiovascular disease and stroke prevention or treatment, or to related clinical and public health problems, including multidisciplinary efforts.  Proposals are encouraged on provider behavior, patient behavior, behavioral outcomes, risk factor outcomes, disease outcomes, cost benefit analyses, efforts to evaluate outcomes of patient care delivery and patient/provider and/or system compliance and adherence to recommendations, as well as pilot clinical research studies that may provide preliminary data for larger-scale investigation. Studies using existing databases are also encouraged.  Ancillary studies or a clearly defined sub-study of an ongoing clinical research study are also encouraged. There must, however, be clear justification that the proposal is a sub-study and not a piece of an already funded project.

20. AMERICAN HEART ASSOCIATION (Cont’d.) Target Audience • Healthcare professional with a masters or post-baccalaureate doctoral degree, including M.P.H., R.N., Pharm.D., M.D., D.O. or Ph.D.   • Interdisciplinary research teams are eligible. • Individuals are not eligible to be the principal investigator if they hold or have held:Certain NIH awards (such as RO1, R21, PO1) • Certain AHA awards (BGIA, SDG, EIA, GIA); or • An award equivalent to any of the above (an independent investigator award) 

21. Repurposing your NIH Grant for a Foundation Submission Positives: • Increases your chances of becoming funded • Saves time and effort when writing and submitting a essentially identical application • Allows you to retain focus on that particular research project Cautions: • If you submit a repurposed NIH grant to another federal agency, e.g. NSF, DOD, DOE, and/or to a foundation, while simultaneously re-submitting to the NIH, make sure you declare your pending sources of private or public funding when you apply. • Agencies expect an applicant to turn down a grant if it overlaps with another one, should both subsequently be funded.

22. Services of the BMC Development Office • Our Foundation Relations and Government Grants (FRGG) team in the BMC Development Office works with BMC investigators to create well-planned proposals specifically tailored to funder interests and guidelines. • We work closely with PIs, administrators and Grants Administration to ensure all submission components are completed in a timely and accurate manner. We will: • Help manage the entire grant writing process • Prospect for other federal and foundation research grant opportunities • Speak with respective Program Officers about potential funding • Tailor project ideas to fit with requests for proposal • Work with BMC Grants Administration; i.e. handle internal documents, assist with financial disclosure forms, broker interdepartmental and external partnerships, assist with InfoEd

23. Services of the BMC Development Office We will also: • Helpadd value to proposal by ensuring all aspects of the RFP are answered within the narrative • Assist with grantsmanship by developing a logic matrix crafted to your research • Draft letters of support • Craft specific aims • Write resource pages • Finalize budget • Provide editing assistance and feedback • Cut down narrative to fit within space requirements • Work with administrators and researchers to ensure quality control • Set up proposal review teams • Assemble, package and submit • Assist with resubmissions and renewals

24. Thank You! • Questions?