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ESOPHAGEAL MOTILITY DISORDERS. DR V JONKER DEPT CARDIOTHORACIC SURGERY. TYPES. Achalasia Diffuse esophageal spasm Hypercontracting esophagus Hypocontracting esophagus Hypertensive LES Secondary motility disorders (related to systemic disease). ACHALASIA. Etiology
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ESOPHAGEAL MOTILITY DISORDERS DR V JONKER DEPT CARDIOTHORACIC SURGERY
TYPES • Achalasia • Diffuse esophageal spasm • Hypercontracting esophagus • Hypocontracting esophagus • Hypertensive LES • Secondary motility disorders (related to systemic disease)
ACHALASIA • Etiology • Incidence 0.5/100 000 • Age 20-50 • Patophysiology • Auerbach plexus destruction • Loss of postganglionic inhibitory neurons
DIAGNOSIS • Clinical • CXray esophagus and pulmonary • Contrast esophagogram
Manometry • Incomplete relaxation of LES • Aperistalsis of the body
Treatment • Reduce pressure gradient • Medical • Botulinum toxin • Pneumatic Dilatation • Esophagomyotomy • Laparoscopy with partial (Dor) wrap • Thoracotomy vs laparotomy • Esophagectomy
DIFFUSE ESOPHAGEAL SPASM • 5% of motility disorders • 50 year female • Pathology • Pathophysiology
Diagnosis • Clinical • Radiographic
Treatment • Exclude IHD • Medical • Dilatation • Botulinum toxin • Extended esophagomyotomy
HYPERCONTRACTING ESOPHAGUS(NUTCRACKER ESOPHAGUS) • High amplitude esophageal contractions • Pathophysiology • 50 year female • Diagnosis • Clinical • Radiological – (N) • Manometry –peristaltic > 180mmHg
Treatment • Similar to DES
OTHER • HIPERTENSIVE LES • Resting pressure > 45mmHg mid-resp • HYPOCONTRACTING ESOPHAGUS • Low amplitude peristalsis • Scleroderma • Treatment – control reflux
SECONDARY MOTILITY DISORDERS • Another systemic disease • Treat underlying cause and GERD • Chaga’s disease • Pseudoachalasia- GEJ ca