Johnson & Johnson’s earthwards Green Product Journey

1. Johnson & Johnson’s earthwardsGreen Product Journey

2. AGENDA J&J’s GreenER Product Design Approach Examples of Green Chemistry

3. World's most comprehensive and broadly based manufacturer of health care products, as well as a provider of related services, for the consumer, pharmaceutical, and medical devices and diagnostics markets. • More than 230 operating companies • Approximately 116,000 employees • Operate in 57 countries • 3 Divisions: Pharmaceuticals, Medical Devices & Diagnostics, and Consumer • $61.1 billion in sales

4. CONSUMER

5. PHARMACEUTICAL

6. MEDICAL DEVICES & DIAGNOSTICS

7. Our Credo We are responsible to the communities in which we live and work and to the world community as well. We must be good citizens – support good works and charities and bear our fair share of taxes. We must encourage civic improvements and better health and education. We must maintain in good order the property we are privileged to use, protecting the environment and natural resources. It’s Our Credo. It’s the right thing to do. It has business value.

8. Healthy People, Healthy Planet, Healthy Business Vision & Strategy Healthy Planet Sustainability Practices 2010 Goals

9. “THE ENVIRONMENT IS THE ULTIMATE HUMAN HEALTH ISSUE”

10. Product Stewardship Vision • What is J&J’s product stewardship vision? • Use of life cycle thinking • Continuous improvement – greenER products • Create business value by meeting customers needs • Deploy new earthwards process • Focus- building on past successes/programs (DfE & HP 2010) • Evaluation of products using a life cycle process • Develop green product attributes • A clear way to demonstrate our greenER products

11. Our Green Product Development Process

13. Energy • Guides, checklists, best practices Materials/Ingredients Chemical look up (DfE) Material Use Reg Summary (DfE) Watch list (DfE) • Water • Guides, checklists, best practices • Compliance • C2P • DfE regulatory metrics • Electronics • Material use • Battery • Waste • Guides, checklists, best practices Life Cycle Thinking Checklist, LCA light tool, examples Packaging Protocol (DfE) Guide (DfE) Plastic selection guide Recognition GreenER product catalog, jnj.com Innovation Guides, best practices

14. DfE Chemical Look Up Tool…ASSESSMENT OF PRODUCT MATERIALS COVERS PRODUCT, PROCESS & PACKAGING

15. Watch List Consumer Products Bisphenol-A Coal Tar (and its derivatives) DEHA GMO containing material Nitromusks Nitrosamines Nonylphenols Organotin Compounds Parabens; butyl & isobutyl PFOA PFAS/PFOS Certain compounds Phthalates (DEHP, DBP, DEP) Polycyclic musks PVC Sodium lauryl sulfate Triclosan High risk materials identified by the PBT Profiler Pharmaceutical Products GMO containing excipients (non-active ingredients) Organotin Compounds Phthalates (DEHP, DBP, DEP) PVC Medical Device Products Antimony trioxide Cadmium Chromium +6 Latex Lead Mercury Nonylphenols Organotin Compounds PBB/PBDE & other Brominated Flame Retardants PFOA Certain PFAS/PFOS compounds Phthalates (DEHP, DBP, DEP) PVC

16. Packaging Antimony trioxide Bisphenol-A Cadmium Chromium +6 DEHA ITX and other photo-initiators Lead Mercury Nonylphenols and ethoxylates Organotin Compounds PBB/PBDE Pentachlorophenol PFOA Certain PFAS/PFOS compounds All Products Known Human Carcinogens (In DfE tool J&J Carcinogen list “k” code) Chlorinated Solvents Endocrine Disrupters – EU Category I & II (In DfE tool EU Endocrine Disruptor list coded I or II) PBT/vPvB Substances (in DfE tool US Persistent Bioaccumulative and Toxic list) Other self-identified materials of significant concern Watch List

18. Id product Project info sheet Pre-requisites Life-cycle screen Improve >10% in 3 of 10 goals Submit for review

19. Id product Project info sheet Pre-requisites Life-cycle screen Improve >10% in 3 of 10 goals Submit for review B O A R D to the

20. The Excel Tool Behind the Scorecard

26. PVC Eliminated (MM kgs)

27. Intelence (etravirine, TMC 125) Green Science success Increased yield and reduced the spent waste solvents; 540,000 liters/yr spent solvent elimination via: Reducing steps; increasing the use of water as solvents; decreasing the use of chlorinated solvents Expected savings of $90MM/yr 60% reduction in the use of methylene chloride in spray drying step via recycling back into the step Solvent Recycle

28. Green Technology: Fractionation Several technologies were evaluated including Reverse Osmosis and Fractionation to further purify polymers used as excipient in coating drug-eluting stents Dramatically increased purity of polymer while reducing the number (toluene and methanol use eliminated) and amount of solvents used 45,000 liters of solvents eliminated & saved $20,000/kg of polymer; a projected savings $2MM/yr

29. 2008 Product Stewardship Excellence Award Winner Category: Green Chemistry Propylene Glycol Hydration Substitution Project By: Vistakon, Jacksonville • Substituted isopropyl alcohol with a propylene glycol in the lens hydration process • Up to 50 tons VOC emission source reduction per year • Up to 212,000 gallons of IPA use reduction per year • Up to 122,000 gallons overall solvent reduction per year • 8,278,000 lb reduction of waste disposal from 2007 to 2008 • Raw material cost savings of $7.7 million per year

30. All new blood glucose meters are RoHS compliant • Cadmium ( Cd ) • Chromium Cr VI • Lead ( Pb ) • Mercury ( Hg ) • Polybrominated Biphenyl ( PBBs ) • Polybrominated Diphenylethers (PBDEs)

31. Corporate Sustainability: Greening our Products Thank you! Al Iannuzzi, Ph.D. Senior Director, Worldwide Environment, Health & Safety Johnson & Johnson 732-524-6382 aiannuz@corus.jnj.com