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Vampires Among Us. Reality in Fiction. By: Blaque Smith. Main Topics. Porphyria Then. Porphyria Now. Porphyria Then…. What where their symptoms?. Sensitivities and other physical ailments. . Flesh is eaten away. Aggression/Mental. Sensitivities and Other Physical Ailments.
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Vampires Among Us Reality in Fiction By: Blaque Smith
Main Topics • Porphyria Then • Porphyria Now
Porphyria Then… What where their symptoms? • Sensitivities and other physical ailments. • Flesh is eaten away. • Aggression/Mental.
Sensitivities and Other Physical Ailments • Sensitivities to sun light • Garlic • Chest and abdominal pains
Flesh is eaten away • Flesh eating toxins • Nose and ears • Lips begin to recede
Aggression/Mental • Violence • Confusion • Anxiety • Irritability • Insomnia
What Happened to Those Infected? • Medical attention • Religion and its leaders • Living their lives
How Their Lives Became Lore • Disfigurement • Light sensitivities • Garlic • Blood remedies • Religious relics
Porphyria Now… Today, scientists have discovered different strains of the virus. • Acute Intermittent Porphyria (AIP) • Porphyria Cutanea Tarda (PCT) • Congenital Erythropoietic Protoporphyria (CEP)
Porpheryins cause changes in heme. • Heme carries oxygen and removed carbon dioxide. • Heme is turned into a toxic substance What is Porphyria?
Acute Intermittent Porphyria (AIP) • What are the symptoms? • When do symptoms appear? • What are the treatments?
Symptoms • Nausea and vomiting • Abdominal pain and cramping • Heart arrhythmia • Seizures • Hallucinations • Depression
When do symptoms occur? • Symptoms generally occur after puberty. • Attacks can last days, even weeks.
Treatments • Heme intravenously. • Hematin • Heme albumin • Heme arginate • Glucose intravenously • Drugs to control symptoms • Pain • Nausea • Anxiety • Insomnia
Porphyria Cutanea Tarda (PCT) -Most common form- • What are the symptoms? • When do symptoms appear? • What are the treatments?
Symptoms • Sun sensitivity • Skin can become fragile • Blisters • Skin thickens • Skin heals slowly • Skin is susceptible to infection
When do symptoms occur? • Not inherited, but acquired
Treatments • Blood removal • Low doses of antimalarial drugs • Chloroquine • Hydroxychloroquine • Radiology imaging
Congenital Erythropoietic Protoporphyria (CEP) -Extremely rare- • What are the symptoms? • When do symptoms appear? • What are the treatments?
Symptoms • Reddish urine • Sun sensitivity • Skin becomes fragile • Blisters • Excess hair growth • Reddish-brown teeth • Hemolytic anemia
When do symptoms occur? • Early infancy • Sun sensitivity • Reddish urine • Acquired later in life
Treatments • Oral beta-carotene • Oral charcoal • Aids porphyrin excretion from stool • Blood transfusions • Splenectomy-removal of splene • Bone marrow transplants
Conclusion • Fear gripped those who didn’t understand. • Through a historical disease folk lore was created. • Better understanding of the disease today.
Bibliography Koppy, Lawrence. (March 2013) “The Vampire Disease” http://suite101.com/article/the-vampire-disease-a163962 Wood, Debra. (2013) “Porphyria” Lifescript; Healthy Living for Women http://www.lifescript.com/health/a-z/conditions_a-z/conditions/p/porphyria.aspx?trans=1&du=1 Elizabeth Bathory (2013) www.elizabethbathory.com Elizabeth Bathory: The Blood Countess www.elizabethbathory.net IMDb www.imdb.com National Human Genome Research Institute www.genome.gove/19016728 Vampire Facts www.vampirefacts.net Vlad the Impaler (2009) www.vladtheimpaler.com