Strengthening global cancer research and global cancer control

1. Strengthening global cancer research and global cancer control Edward L. Trimble, MD, MPH Director, Center for Global Health National Cancer Institute

2. NCI CGH Signature Themes • Cancer control planning and implementation • Cancers associated with chronic infection • Common risk factors for NCDs, especially tobacco • Strengthening research in ecological-niche cancers • Strengthening global research networks • Strengthening global health activities through NCI-designated Cancer Centers • Building partnerships

3. 2013 Cancer Center Competitive Supplement • To promote cancer research and to increase research capacity in LMICs through collaborations or research partnerships between NCI-Designated Cancer Centers and foreign institutions • One-year pilot study

4. SCOPE • Basic, translational or clinical research • Training and capacity building • Informatics, data managing and sharing • Biorepositories establishment and management • Retrospective or prospective studies, assay development • HIV-associated malignancies; integration of HIV programs that benefit cancer patients

5. RFP 2013 STATISTICS • Contract mechanism • $200K Total Cost • 43 proposals received • 42 proposals reviewed • 15 proposals to be awarded • 5 currently awarded (as of March 7, 2014) • 5 at sites for signature • 3 in negotiations • 2 pending clearance at FIC

6. Future considerations • How to encourage NCI Cancer Centers and universities working in same country or region to work together, both in cancer and across diseases? • How to encourage US Cancer Centers to work with other developed world universities and institutions? • Trans-NIH approach? • Health surveillance, training, research, career development, research to policy & public health practice, etc.

7. This is for title Partnership with Consortium of Universities for Global Health (CUGH) • This is for text • Raise the profile for global cancer research and control • Build collaborations with global health professionals focused on other disease areas • Strengthen the evidence-base for global health and cancer programs • Translate research findings into public policy and clinical practice

8. This is for title CUGH Annual Conference 2013 • This is for text • Dr. Doug Lowy represented NCI on NIH Panel along with Dr. Anthony Fauci, Dr. Roger Glass, and other NIH global health research leaders • Held satellite cancer meeting – Global Cancer Research Day • Presentations on future directions for global health and non-communicable disease control • Interactive discussions between global cancer and global health professionals

9. This is for title Upcoming CUGH Annual Conference 2014 • This is for text • Dr. Harold Varmus to represent NCI on NIH Panel • NCI to organize Cervical Cancer Implementation Research Panel • Organizing satellite meeting to CUGH Conference for the second year – Symposium on Global Cancer Research

10. This is for title Symposium on Global Cancer Research 2014 • This is for text • Focus areas: • International research partnerships • Integrating science and policy • Poster session showcasing quality global cancer research projects and workshops • Travel awards and oral presentations for top three abstracts from LMIC applicants

11. Strengthening Partnerships • NIH: Fogarty, NHLBI, NIAID, etc. • HHS: Office of Global Affairs, CDC • State: Bureau of Oceans and International Environmental & Scientific Affairs, PEPFAR, USAID • Professional societies: ASCO, ASTRO, ACOS, SGO, SSO, SIOP, USCAP, etc • Advocacy groups: ACS, Susan Komen, LiveStrong, etc.

12. Strengthening Partnerships • WHO: International Agency for Research on Cancer, PAHO, EURO, etc. • International Union for Cancer Control (UICC) • Cancer Research UK, Kings College London Institute of Cancer Policy, etc. • French NCI, Brazilian NCI, Cancer Institute of Chinese Academy of Medical Sciences, Tata Memorial Hospital, etc.

13. Global Cancer Research Map A Partnership between NCI’s Center for Global Health and Global Oncology!

14. Map of Cancer Research & Control Activities • USG: NCI, Fogarty, other NIH; CDC, etc • NCI-Designated Cancer Centers • ASCO, UICC, and other NGOs • Wellcome Trust, Cancer Research UK, Kings College London, French NCI, Dutch Cancer Society, etc • European Cancer Centers • Global pediatric cancer efforts

15. Workshops & Mtgs: Spring 2014 • Middle East Cancer Consortium/ Turkish Cancer Week, Ankara • Southeast Asia Regional Cancer Control Planning Workshop, Kuala Lumpur • US-Latin American Cancer Research Network Strategy Meeting, Bethesda • Caribbean Public Health Agency-NCI-CDC workshop on cancer research & control, Trinidad-Tobago

16. Workshops & Mtgs: Spring 2014 • World Health Assembly, Geneva • East Asia/ Southeast Asia regional cancer registry workshop (NCI, CDC, CICAMS), Shanghai • Pan-American Health Organization (PAHO)-NCI-CDC-industry workshop on integrating HPV diagnostics into public health cervical cancer screening, Washington, DC • PAHO-NCI-CDC workshop on combined NCD health surveillance, Washington, DC

17. Workshops & Mtgs: Spring 2014 • East Africa Regional Cancer Control Planning Forum, Lusaka, Zambia • Country Cancer Research and Control Stakeholders Meeting, Naivasha, Kenya • Burkitts Lymphoma Research Network Kick-off Meeting, Chicago (at ASCO)

18. Contact information • Telephone: +1-240-276-5796 • Email: tt6m@nih.gov • Twitter: @NCIGlobalHealth • Web: www.cancer.gov/globalhealth