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Hematopathology Laboratory Tata Memorial Hospital

Hematopathology Laboratory Tata Memorial Hospital. P.G.SUBRAMANIAN Associate Professor & Officer Incharge , Hematopathology Laboratory Tata Memorial Hospital. Immunophenotyping . ACADEMIC ACTIVITIES A) Education / Training Programme (2012).

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Hematopathology Laboratory Tata Memorial Hospital

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  1. Hematopathology Laboratory Tata Memorial Hospital P.G.SUBRAMANIAN Associate Professor & Officer Incharge, Hematopathology Laboratory Tata Memorial Hospital

  2. Immunophenotyping

  3. ACADEMIC ACTIVITIESA) Education / Training Programme (2012) • The laboratory has started following courses • Hematopathology fellowship program. It is 2 year post MD training program in hematopathology • Immunophenotyping – Bench to Clinic, Course for Technician – One course every year • Immunophenotyping – Bench to Clinic, Course for Pathologists – One course every year

  4. Total Publications Pubmed Indexed 2011 – 4 2010 – 5 2009 – 10

  5. Publications in last 5 years with flow cytometry as predominant role in study • Gadage VS, Subramanian PG, Galani KS, Sehgal KK, Johari SP, Ghogale VS, Badrinath Y, Ashok K, Gujral S. Leukemic phase of anaplastic lymphoma kinase positive, anaplastic large cell lymphoma. Indian J PatholMicrobiol. 2011 Jul-Sep;54(3):599-602. PubMed PMID: 21934233. • Tembhare PR, Subramanian PG, Sehgal K, Yajamanam B, Kumar A, Gadge V, Inamdar N, Gujral S. Immunophenotypic profile of plasma cell leukemia: a retrospective study in a reference cancer center in India and review of literature. Indian J PatholMicrobiol. 2011 Apr-Jun;54(2):294-8. Review. PubMed PMID: 21623077. • Gujral S, Polampalli S, Badrinath Y, Kumar A, Subramanian PG, Nair R, SengarM, Nair C. Immunophenotyping of mature T/NK cell neoplasm presenting as leukemia. Indian J Cancer. 2010 Apr-Jun;47(2):189-93. PubMed PMID: 20448385.

  6. Publications in last 5 years with flow cytometry as predominant role in study • Gujral S, Polampalli SN, Badrinath Y, Kumar A, Subramanian PG, Nair R, Gupta S, Sengar M, Nair C. Immunophenotyping of mature B-cell non Hodgkin lymphoma involving bone marrow and peripheral blood: critical analysis and insights gained at a tertiary care cancer hospital. Leuk Lymphoma. 2009 Aug;50(8):1290-300. PubMed PMID: 19811331. • SehgalK, Badrinath Y, Tembhare P, Subramanian PG, Talole S, Kumar A, Gadage V, Mahadik S, Ghogale S, Gujral S. Comparison of platelet counts by CellDyn Sapphire (Abbot Diagnostics), LH750 (Beckman Coulter), ReaPanThromboimmunoplatelet method (ReaMetrix), and the international flow reference method, in thrombocytopenic blood samples. Cytometry B ClinCytom. 2010 Jul;78(4):279-85. PubMed PMID: 20229505.

  7. Publications in last 5 years with flow cytometry as predominant role in study • Gujral S, Subramanian PG, Dasgupta A. Diversity amongst various guidelines for immunophenotyping. Cytometry A. 2009 Jul;75(7):560-1. PubMed PMID: 19504568. • Gujral S, Polampalli S, Badrinath Y, Kumar A, Subramanian PG, Raje G, Amare P, Arora B, Banavali SD, Nair CN. Clinico-hematological profile in biphenotypic acute leukemia. Indian J Cancer. 2009 Apr-Jun;46(2):160-8. PubMed PMID: 19346652. • Gujral S, Tembhare P, Badrinath Y, Subramanian PG, Kumar A, Sehgal K. Intracytoplasmic antigen study by flow cytometry in hematolymphoid neoplasm. Indian J PatholMicrobiol. 2009 Apr-Jun;52(2):135-44. Review. PubMed PMID: 19332897. • Gujral S, Badrinath Y, Kumar A, Subramanian PG, Raje G, Jain H, Pais A, AmreKadam PS, Banavali SD, Arora B, Kumar P, HariMenon VG, Kurkure PA, Parikh PM, Mahadik S, Chogule AB, Shinde SC, Nair CN. Immunophenotypic profile of acute leukemia: critical analysis and insights gained at a tertiary care center in India. Cytometry B ClinCytom. 2009 May;76(3):199-205. PubMed PMID: 18803279.

  8. Publications in last 5 years with flow cytometry as predominant role in study • Gujral S, Agarwal A, Gota V, Nair R, Gupta S, Pai SK, Sanger M, Shet T, Subramanian PG, Muckaden M, Laskar S. A clinicopathologic study of mantle cell lymphoma in a single center study in India. Indian J PatholMicrobiol. 2008 Jul-Sep;51(3):315-22. PubMed PMID: 18723950. • Gujral S, Subramanian PG, Patkar N, Badrinath Y, Kumar A, Tembhare P, Vazifdar A, Khodaiji S, Madkaikar M, Ghosh K, Yargop M, Dasgupta A. Report of proceedings of the national meeting on "Guidelines for Immunophenotyping of Hematolymphoid Neoplasms by Flow Cytometry". Indian J PatholMicrobiol. 2008 Apr-Jun;51(2):161-6. PubMed PMID: 18603672.

  9. Immunophenotyping results

  10. Ongoing projects • ALL MRD • Plasma Cell dyscrasias Immunophenotyping • CD200 in B cell neoplasms • Applicability of WHO 2008 Classification in our centre • AML MRD

  11. CD200 in B Cell NHL

  12. Future plans • Setting up and running a self sustaining EQA program • Collaborative multi centric projects in finding newer markers in defining neoplasms and in disease monitoring and prognostication • Defining normal ranges for T cell subsets for use in health and disease

  13. Thank You

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