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Supplemental Figure 1

Frozen invasive IPMN. FFPE invasive IPMN. Frozen non-invasive IPMN. P=0.10. FFPE non-invasive IPMN. 22. 20. 18. 16. 14. 12. miR-21 expression (2 - Δ Ct ). 10. 8. 6. 4. 2. 0. Frozen. FFPE. IPMN samples. Supplemental Figure 1. A. 80. 60. Density (%). 40. 20. 0.0. 0.0. 5.

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Supplemental Figure 1

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  1. Frozen invasive IPMN FFPE invasive IPMN Frozen non-invasive IPMN P=0.10 FFPE non-invasive IPMN 22 20 18 16 14 12 miR-21 expression (2-ΔCt) 10 8 6 4 2 0 Frozen FFPE IPMN samples Supplemental Figure 1

  2. A 80 60 Density (%) 40 20 0.0 0.0 5 10 15 20 25 30 B 30 25 20 Density (%) 15 10 5 0.0 0.0 5 10 15 20 C 60 40 Density (%) 20 0.0 0.0 5 10 15 20 25 microRNA expression values (2-ΔCt) Supplemental Figure 2

  3. A miR-21 miR-101 miR-155 B 100 P=0.074 80 60 Cumulative Percentage 40 20 DFS (Time, months) 0.0 0.0 25 50 75 100 125 100 C 80 P=0.084 60 Cumulative Percentage 40 20 OS (Time, months) 0.0 Supplemental Figure 3 0.0 25 50 75 100 125

  4. A B C D E F G H Supplemental Figure 4

  5. Supplemental Figure 5

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