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Urinary system. Tutorial. Antibody mediated glomerular disease. B - linear pattern C - granular pattern. Causes of the nephrotic syndrome. Proteinuria> 3.5 g of urinary protein:hypoalbuminaemia <3g/dl: oedema, hyperlipidaemia and lipiduria. A – minimal change B – membranous GN.
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Urinary system Tutorial
Antibody mediated glomerular disease B - linear pattern C - granular pattern
Causes of the nephrotic syndrome Proteinuria> 3.5 g of urinary protein:hypoalbuminaemia <3g/dl: oedema, hyperlipidaemia and lipiduria
A – minimal change B – membranous GN
Quiz A 12 year old boy develops oliguria
RPKD mutations in chr 6p
DPKD • Seen in 1 in 500 to 1000 people • Accounts for 10% of cases of CRF • Caused by inheritance of 2 AD genes • PKD 1 chr 16 (90% cases) polycystin 1 • PKD 2 chr 4 (10% cases) polycystin 2
Hereditary nephritis (Alport’s syndrome)