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Immunity Unit Day 2

Immunity Unit Day 2. Every path has its puddle. English proverb. Today’s Agenda. Lymph Notes on obj. 2, 3, 4 Color nodes Notes on objective 5-8 Practice. A T cell infected with HIV. Obj. 2 Lymph Transport: Flow of lymphatic fluid. The flow of lymph is slow

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Immunity Unit Day 2

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  1. Immunity Unit Day 2 Every path has its puddle. English proverb

  2. Today’s Agenda • Lymph Notes on obj. 2, 3, 4 • Color nodes • Notes on objective 5-8 • Practice

  3. A T cell infected with HIV

  4. Obj. 2 Lymph Transport: Flow of lymphatic fluid • The flow of lymph is slow • The flow is maintained by skeletal contractions, pressure changes in the thoracic and contractions of the lymph vessels. • Valves prevent backflow. Lymphatic capillaries are exceptionally permeable, admitting proteins and particles from the interstitial space.

  5. Circulation in the Lymph Nodes • Lymph fluid enters node through afferent lymphatic vessels. • Exits lymph node through efferent lymphatic vessels. • There are fewer efferent vessels allowing lymph fluid to stagnate (stay longer) in the lymph node before exiting, allowing time for cleaning this lymph fluid.

  6. Other Lymphoid Organs:These organs don’t filter but do contain macrophages and lymphocytes. • Spleen: • Destroys old or defective red blood cells • Stores platelets • Acts as a hematopoietic site in the embryo and in sever cases of anemia

  7. Other Lymphoid Organs:These organs don’t filter but do contain macrophages and lymphocytes. • Thymus gland • Most functional during youth • Its hormones cause T lymphocytes to become immuno competent.

  8. Other Lymphoid Organs:These organs don’t filter but do contain macrophages and lymphocytes. • Tonsils and Peyer’s patches • Small organs known collectively ast GALT (gut-associated lymphatic tissues). • Prevent pathogens in the respiratory and digestive tract from going through the mucous membrane lining

  9. Take the next 10 minutes to color your lymph node

  10. Obj. 5 Nonspecific Defenses: things your body uses to defend against ANYTHING • 1. Skin & mucous membranes • 2. Phagocytic cells • 3. Natural killer cells • 4. Inflammatory response • 5. Antimicrobial substances • 6. Fever

  11. Obj. 5 Nonspecific Defenses: things your body uses to defend against ANYTHING • 1. Skin & mucous membranes M U C U S L O W p H S A L I V A T E A R S

  12. Bacterial leprosy infection just under skin.

  13. “border line leprosy—numb centers

  14. Obj. 5 Nonspecific Defenses: things your body uses to defend against ANYTHING • 1. Skin & mucous membranes • 2. Phagocytic cells--macrophages

  15. Obj. 6 • 1. Skin & mucous membranes • 2. Phagocytic cells – engulf and destroy pathogens • 3. Natural killer cells – attack and lyse body cells infected by viruses or that are cancerous.

  16. Obj. 7 Inflammatory response • 1. Skin & mucous membranes • 2. Phagocytic cells • 3. Natural killer cells • 4. Inflammatory response • damaged tissues release histamines • Histamines make vessels leaky, releasing phagocytes & clotting factors • Phagocytes engulf bacteria • Platelets form clots

  17. Obj. 7

  18. Obj. 5 Nonspecific Defenses: things your body uses to defend against ANYTHING • 1. Skin & mucous membranes • 2. Phagocytic cells • 3. Natural killer cells • 4. Inflammatory response • 5. Antimicrobial substances • Interferon • Complement proteins

  19. Obj. 8 Fever • 1. Skin & mucous membranes • 2. Phagocytic cells • 3. Natural killer cells • 4. Inflammatory response • 5. Antimicrobial substances • 6. Fever • Macrophages release pyrogens • Hypothalamus elevates temperature • Liver & spleen supply less iorn • Bacteria don’t grow well without iron • Metabolism increases speeding repair. 105 98.6

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