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Asexual Reproduction. Mitosis. Mitosis is the process in which the nucleus divides to form two new nuclei. How does mitosis differ in plants and animals?. 1. How do little elephants grow up to be BIG elephants?. Why do animals shed their skin?.
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Asexual Reproduction Mitosis Mitosis is the process in which the nucleus divides to form two new nuclei. How does mitosis differ in plants and animals? 1
The process of asexual reproduction begins after a sperm fertilizes an egg.
Three reasons why cells reproduce by asexual reproduction: 1. Growth 2. Repair 3. Replacement
Animated Mitosis Cycle http://www.cellsalive.com/mitosis.htm • Interphase • Prophase • Metaphase • Anaphase • Telophase & Cytokinesis
Interphaseoccurs before mitosis begins • Chromosomes are copied (# doubles) • Chromosomes appear as threadlike coils (chromatin) at the start, but each chromosome and its copy(sister chromosome) change to sister chromatids at end of this phase CELL MEMBRANE Nucleus Cytoplasm
4 single-stranded chromosomes Forms of DNA Unwound DNA • Chromatin • Chromosomes • Chromatids DNA wound or coiled • Replicated DNA – held together by centromeres • 2 chromosomes – count centromeres • 4 chromatids
Interphase Plant Cell Animal Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Prophase 1st step in Mitosis • Mitosis begins (cell begins to divide) • Centrioles(or poles) appear and begin to move to opposite end of the cell. • Spindle fibers form between the poles. • Chromosomes are visible Centrioles Sister chromatids Spindle fibers
Prophase Plant Cell Animal Cell Spindle fibers Centrioles Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Metaphase 2nd step in Mitosis • Chromatids (or pairs of chromosomes) attach to the spindle fibers. • They line up in the “middle” or equator Centrioles Spindle fibers
Metaphase Plant Cell Animal Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Anaphase 3rdstep in Mitosis • Chromatids (or pairs of chromosomes) separate and begin to move apart to opposite ends (“poles”) of the cell. Centrioles Spindle fibers
Anaphase Plant Cell Animal Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Telophase4th step in Mitosis • Two new nuclei form. • Chromosomes appear as chromatin (threads rather than rods). • Mitosis ends. Nuclei Nuclei Chromatin
Telophase Plant Cell Animal Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Cytokinesisoccurs after mitosis • Cell membrane moves inward to create two daughter cells – each with its own nucleus with identical chromosomes. • Cells are identical to each other and to the original only smaller
- Cell Division The Cell Cycle 23
MitosisAnimation http://www.cellsalive.com/mitosis.htm
CANCERuncontrolled mitosis Skin cancer - the abnormal growth of skin cells - most often develops on skin exposed to the sun. Cell that reproduce by asexual reproduction reproduce constantly.
Why would cells just make copies? If DNA gets damaged, cells stop listening to correct instructions – make WRONG protein (enzymes) mutations – changes in DNA bases Mutagens (carcinogens) – cause mutations: • cigarette smoke • pollution • age • Genetics • heat • UV radiation • chemical exposure • benzene, toluene, asbestos • radiation exposure
When is mitosis a BAD thing When cells reproduce & they are not needed these cells take over organs, but don’t do the right job they just keep making copies “starve” other cells/tissues cancer – uncontrolled mitosis damages organs
Tumors Benign tumor abnormal cells remain at original site as a lump most do not cause serious problems &can be removed by surgery
Tumors Malignant tumor cells leave original site - metastasizes carried by blood system to other tissues start more tumors damage functions of organs throughout body